Superficial myofibroblastoma of the lower female genital tract is a rare, recently described tumor, which has a distinctive clinico-pathological profile. We report a 63-year old patient who presented with a polypoid vaginal mass. Histopathological examination revealed a moderately cellular tumor composed of bland spindled and stellate cells. Immunohistochemical investigations showed reactivity for vimentin, desmin and CD34. This tumor should be differentiated from other mesenchymal lesions, which may arise in this area.

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