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http://dx.doi.org/10.1016/j.juro.2007.06.002 | DOI Listing |
Cureus
December 2024
Radiodiagnosis, MNR Medical College and Hospital, Sangareddy, IND.
Zinner syndrome is an extremely uncommon congenital anomaly of the male urogenital tract. It is attributed to an embryological anomaly that arises in the distal segment of the mesonephric or Wolffian duct. It is the inadequate migration of the ureteric bud that contributes to the failure of differentiation of the metanephric blastema, which ultimately results in ipsilateral renal agenesis and atresia of the ejaculatory duct.
View Article and Find Full Text PDFAsian J Surg
December 2024
Department of Radiology, the Second Affiliated Hospital of Dalian Medical University, 467 Zhong Shan Road, Dalian, 116023, China. Electronic address:
Development
December 2024
Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Growth arrest specific 1 (GAS1) is a key regulator of mammalian embryogenesis, best known for its role in hedgehog (HH) signaling, but with additional described roles in the FGF, RET, and NOTCH pathways. Previous work indicated a later role for GAS1 in kidney development through FGF pathway modulation. Here, we demonstrate that GAS1 is essential for both mesonephrogenesis and metanephrogenesis - most notably, Gas1 deletion in mice results in renal agenesis in a genetic background-dependent fashion.
View Article and Find Full Text PDFHinyokika Kiyo
August 2024
The Department of Urology, Yokohama City University Hospital.
Metanephric adenoma is an extremely rare disease. We describe two cases of metanephric adenoma. Case 1 : A 17-year-old male adolescent developed gross hematuria, and urinalysis revealed positive protein and occult blood.
View Article and Find Full Text PDFComp Biochem Physiol C Toxicol Pharmacol
November 2024
Developmental Integrative Biology Group, The University of North Texas, 1155 Union Circle, Denton, TX 76203, USA. Electronic address:
Atenolol is a widely prescribed β-cardioselective blocker. We studied atenolol effects on cardiac and renal development in day 18 (D18) chicken embryos. Embryos were dosed with atenolol (3 μg atenolol/g estimated embryo mass) for three days during one of the mesonephric kidney stage (D7-D9), mesonephric-metanephric stage (D11-D13), or metanephric stage (D15-D17), and then sampled on D18.
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