The ability of bacterial DNA methyltransferases Alu I, Cfr I, Cfr 6, Cfr 10, Eco RI, Eco RII, Msp I, Mva I, Pvu I, Pvu II, and Sau 3A to use methyl-cobalamine and methyl-methionine as cofactors of DNA methylation in vitro. These bacterial DNA methyl transferase used methyl-cobalamine, but not methylmethionine for DNA methylation.
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