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| http://dx.doi.org/10.1503/cmaj.070811 | DOI Listing |
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Clinical Characteristics of Virologically Confirmed Respiratory Syncytial Virus in English Primary Care: Protocol for an Observational Study of Acute Respiratory Infection.
JMIR Res Protoc
January 2025
Clinical Informatics and Health Outcomes Research Group, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Background: There are gaps in our understanding of the clinical characteristics and disease burden of the respiratory syncytial virus (RSV) among community-dwelling adults. This is in part due to a lack of routine testing at the point of care. More data would enhance our assessment of the need for an RSV vaccination program for adults in the United Kingdom.
View Article and Find Full Text PDFPolygenic Risk Score Added to Conventional Case Finding to Identify Undiagnosed Chronic Obstructive Pulmonary Disease.
JAMA
January 2025
Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Importance: Chronic obstructive pulmonary disease (COPD) is often undiagnosed. Although genetic risk plays a significant role in COPD susceptibility, its utility in guiding spirometry testing and identifying undiagnosed cases is unclear.
Objective: To determine whether a COPD polygenic risk score (PRS) enhances the identification of undiagnosed COPD beyond a case-finding questionnaire (eg, the Lung Function Questionnaire) using conventional risk factors and respiratory symptoms.
Insights into balloon pulmonary angioplasty and the WHO functional class of chronic thromboembolic pulmonary hypertension patients: findings from the CTEPH AC registry.
Cardiovasc Interv Ther
January 2025
Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan.
Advances in chronic thromboembolic pulmonary hypertension (CTEPH) treatment have improved prognosis, shifting focus towards symptom management. This study aimed to identify factors influencing the World Health Organization functional class (WHO-FC) in CTEPH patients. The CTEPH AC registry is a prospective, multicenter database from 35 Japanese institutions, analyzing data from August 2018 to July 2023.
View Article and Find Full Text PDFDiscriminating between the maxillary tuberosity and the alveolar tuberosity- a critical pictorial review.
Surg Radiol Anat
January 2025
Division of Anatomy, Department 1, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, Bucharest, RO-020021, Romania.
Purpose: The maxillary tuberosity, a critical anatomical landmark in dentistry and maxillofacial surgery, is burdened by terminological confusion. This inconsistency hampers clinical practice and communication across disciplines.
Method: Different resources were used to argue for the necessity of standardising the terminology related to maxillary tuberosity to enhance diagnostic precision and ultimately improve patient outcomes.
Upper airway changes after orthognathic surgery in patients with skeletal class III high-angle malocclusion and mandibular deviation.
Clin Oral Investig
January 2025
College of Stomatology, Dalian University, Dalian, Liaoning, 116622, China.
Objectives: This study analyzed the differences in the upper airway of patients with skeletal Class III high-angle malocclusion with and without mandibular deviation, and further investigated whether there are differences in the changes in upper airway space after orthognathic surgery between the two groups.
Materials And Methods: 15 patients with skeletal Class III high-angle malocclusion and mandibular deviation, and 15 patients without mandibular deviation were selected to explore the impact of mandibular deviation on the upper airway. Additionally, 16 patients with mandibular deviation undergoing orthodontic-orthognathic combined treatment, and 13 patients without mandibular deviation, were selected to investigate the differences in the changes in upper airway space after orthognathic surgery between the two groups.
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