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The Development of Opioid Vaccines as A Novel Strategy for the Treatment of Opioid Use Disorder and Overdose Prevention.
Int J Neuropsychopharmacol
January 2025
Department of Psychiatry and Psychology, Mayo Clinic; Rochester, Minnesota, USA.
Opioid use disorder (OUD) affects over 40 million people worldwide, creating significant social and economic burdens. Medication for opioid use disorder (MOUD) is often considered the primary treatment approach for OUD. MOUD, including methadone, buprenorphine, and naltrexone is effective for some, but its benefits may be limited by poor adherence to treatment recommendations.
View Article and Find Full Text PDFBoosting Dietary Compliance After Bariatric Surgery: Winning Tactics for Patients.
J Eval Clin Pract
February 2025
Department of Pancreatic and Metabolic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China.
Background: Bariatric metabolic surgery has emerged as a pivotal intervention for managing obesity, with strict adherence to postoperative nutritional guidelines being paramount for patient outcomes. This study seeks to evaluate dietary compliance levels and the factors that influence them among patients who have undergone bariatric surgery, offering insights to enhance clinical strategies.
Method: Our research encompassed patients who underwent bariatric metabolic surgery at our institution from February 2022 to December 2023.
Retrospective Cohort Study: Scope for Improvement-Barriers to Post-Polypectomy Surveillance in the Integrated Technologies for Improved Polyp Surveillance Cohort.
Aliment Pharmacol Ther
January 2025
School of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Wolfson Wohl Cancer Research Centre, Garscube Estate, Glasgow, UK.
Background: Adherence to post-polypectomy surveillance is poor despite evidence that it is associated with lower risk of future colorectal cancer.
Methods: We evaluated 6,210 bowel screening participants between 2009-2016 in NHS Greater Glasgow and Clyde to assess potential barriers to post-polypectomy surveillance.
Results: Increasing deprivation (Scottish Index of Multiple Deprivation quintile 1 vs 5; OR 1.
"She tells me the HIV is eating my brains": barriers and facilitators to antiretroviral therapy adherence among Eswatini adolescents living with HIV.
AIDS Care
February 2025
Division of Epidemiology and Social Sciences, Institute for Health and Equity, Medical College of Wisconsin, Milwaukee, WI, USA.
Despite the successful rollout of antiretroviral therapy (ART) and positive ART outcomes in the Kingdom of Eswatini, adolescents still present poor ART outcomes including low viral load suppression and suboptimal ART adherence. The aim of the study was to explore the perceptions of adolescents living with HIV (ALHIV) on the barriers and facilitators to ART adherence in Eswatini. We conducted a qualitative study using in-depth interviews among 29 ALHIV and on ART in Eswatini in December 2023.
View Article and Find Full Text PDFMagnitude of Depression and Associated Factors in Women Living With HIV in Northwest, Ethiopia: Mediation Analysis.
AIDS Res Treat
January 2025
Department of Health Promotion and Behavioral Sciences, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Depression in women living with HIV (WLWHIV), is one of the most common public health concerns worldwide. Depression has a negative impact on antiretroviral therapy (ART) adherence, quality of life, poor HIV treatment outcomes, and mortality. However, there is a paucity of evidence in low-income countries such as Ethiopia in WLWHIV.
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