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Co-infections with Bordetella bronchiseptica in canine: A systematic review and meta-analysis.
Vet Immunol Immunopathol
January 2025
Department of Infectious Disease, College of Veterinary Medicine, Seoul National University, Seoul, Korea; Research Institute for Veterinary Science and BK21, Seoul National University, Seoul, Korea. Electronic address:
Background: Bordetella bronchiseptica is a primary pathogen in canine infectious respiratory disease (CIRD), or kennel cough, capable of independently causing respiratory illness and contributing significantly to co-infections with other viral and bacterial agents. Despite its critical role in disease transmission and persistence, the epidemiology of B. bronchiseptica in CIRD remains poorly understood.
View Article and Find Full Text PDFPradofloxacin Minimum Inhibitory Concentration Profiling of Isolates: Insights into Antimicrobial Susceptibility in Swine.
Pathogens
January 2025
Elanco Animal Health, Greenfield, IN 46140, USA.
This study evaluated the minimum inhibitory concentration (MIC) of pradofloxacin against various swine respiratory pathogens, including , , , , and (), associated with disease in swine. This research was conducted in two phases: the initial phase examined isolates from the lungs that could be either commensal or pathogenic, while the second phase focused on systemic strains that spread from the respiratory tract to the brain. The pradofloxacin MIC values of the second phase were within the MIC range of the initial phase, with MIC and MIC values highlighting its potential as an effective antimicrobial agent.
View Article and Find Full Text PDFOreochromicin-2 shows antimicrobial and immunostimulant effect against respiratory pathogens in pigs.
Res Vet Sci
December 2024
Metabolic Modifiers for Aquaculture, Agricultural Biotechnology Department, Center for Genetic Engineering and Biotechnology (CIGB), 31st Avenue and 190, Havana 10600, Cuba. Electronic address:
Article Synopsis
- Porcine respiratory diseases significantly affect pig production, with common pathogens like Streptococcus suis and Pasteurella multocida also posing risks to human health.
- The overuse of traditional antibiotics has led to antimicrobial resistance, highlighting the need for alternative treatments such as antimicrobial peptides (AMPs).
- Oreochromicin-2 (Oreoch-2), an AMP from fish, showed promising results in reducing bacterial loads and improving health in pigs, making it a potential candidate for treating respiratory diseases in swine.
Lonidamine, a Novel Modulator for the BvgAS System of Bordetella Species.
Microbiol Immunol
December 2024
Department of Molecular Bacteriology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.
The Gram-negative bacteria Bordetella pertussis, B. parapertussis, and B. bronchiseptica cause respiratory diseases in various mammals.
View Article and Find Full Text PDFComparative analysis of antimicrobial resistance and genetic diversity of isolates obtained from swine within the United States.
Front Microbiol
November 2024
National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA, United States.
Introduction: is bacterial pathogen that is pervasive in swine populations and serves multiple roles in respiratory disease.
Methods: This study utilized whole-genome sequencing (WGS) analysis to assess the sequence type (ST), identify the genetic diversity of genes predicted to encode regulatory and virulence factors, and evaluated any potential antimicrobial resistance harbored by isolates obtained from swine within the U.S.
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