[The impact of resistant strains of Mycobacterium tuberculosis on relapse of tuberculosis].

Med Pregl

Institut za plućne bolesti i tuberkulozu, Klinicki centar Srbije, Beograd.

Published: August 2007

AI Article Synopsis

  • Relapses of tuberculosis are uncommon and occur two or more years after completing previous treatment, with a study showing 141 affected patients having an average age of 46.2 years.
  • Relapses were observed about 11.3 years post-treatment, primarily in patients with pulmonary tuberculosis; resistance to antituberculotic agents was a significant factor, with varying levels of drug resistance noted among the patients.
  • The study emphasizes the critical need to address resistant strains of mycobacterium tuberculosis and ensure appropriate medical treatment to achieve full recovery in relapsing patients.

Article Abstract

Introduction: Relapses of tuberculosis are fairly rare nowdays and they represent the onset of tuberculosis two, or more than two years after completion of previous treatment.

Material And Methods: In the previous period, relapses of tuberculosis occurred in 141 patients (87 male and 54 female). Their mean age was 46.2 years.

Results: Relapses of tuberculosis occurred after 11.3 years, on average. All patients presented with pulmonary tuberculosis, and two patients also had pulmonary and extrapulmonary tuberculosis (bones). Resistance was one of the statistically significant factors for relapse of tuberculosis. Resistance to one antituberculotic agent was most common--8 patients, resistance to two drugs--4 patients, resistance to three drugs--4 patients, resistance to four drugs in 5 patients. Due to these findings on resistant strains of mycobacterium tuberculosis, a huge number of patients with relapses of tuberculosis had full recovery and completed the treatment.

Conclusion: The importance of resistant strains of mycobacterium tuberculosis is really huge in our conditions. The findings of these resistant strains of mycobacterium tuberculosis and adequate medical treatment are obligatory nowadays.

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http://dx.doi.org/10.2298/mpns0612522vDOI Listing

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