Background: The need for a safer lower-lid blepharoplasty procedure than the classic subciliary approach has long been recognized. In 1996, de la Plaza and de la Cruz first theorized septal suturing via a transconjunctival approach that preserves both muscle and infraorbital fat. This is the first report of a series of patients treated with this technique. The transconjunctival approach can avoid the complications of "scleral show" and changes in the shape of the aperture that are associated with the subciliary/muscle cutting approach to the fat pads.
Methods: Transconjunctival septal suturing of the middle and medial fat bags was used to treat 78 consecutive patients (72 women and six men) with visible bulging fat of the lower eyelids. Some patients underwent simultaneous resection of fat from the lateral pad.
Results: Bulging fat in the middle and medial compartments was eliminated without overtreatment or undertreatment. Substantial but not total improvement in tear trough deformity was often observed. Aperture shape and lid level were preserved.
Conclusions: The results achieved with this series of patients indicate that transconjunctival suture repair of the orbital septum is a safe, predictable, and effective treatment for bulging fat of the medial and middle fat pads of the lower eyelid. Changes in aperture shape and lid level can be avoided without the need for simultaneous lid-tightening procedures.
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http://dx.doi.org/10.1097/01.prs.0000275182.34994.dd | DOI Listing |
Mediastinum
July 2024
Department of Radiology, Inje University Sanggye Paik Hospital, Seoul, Korea.
Background: Thymic cysts can be classified as congenital or acquired. Most thymic cysts do not change in size over a short period of time. Although very rare, thymic cyst rupture is associated with serious complications, such as mediastinal hemorrhage and hemothorax.
View Article and Find Full Text PDFBiomed Chromatogr
February 2025
Clinical Pharmacology Research Center, Peking Union Medical College Hospital, State Key Laboratory of Complex Severe and Rare Diseases, NMPA Key Laboratory for Clinical Research and Evaluation of Drug, Beijing Key Laboratory of Clinical PK & PD Investigation for Innovative Drugs, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Deoxycholic acid (DCA) injection is applied in treating moderate to severe submental bulge or facial fullness caused by excessive submental fat accumulation. Using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) technology, which was swiftly, precisely, and reliably confirmed, DCA was determined in human plasma with low quantification limits of 56 ng/mL. We selected six healthy individual blank human plasma with low concentrations of endogenous DCA and mixed them to prepare standard curve samples.
View Article and Find Full Text PDFBMC Pediatr
December 2024
Department of Pediatric and Neonatal Intensive Care, University Children's Hospital, Belgrade, 11000, Serbia.
Background: Familial chylomicronemia syndrome (FCS) is a rare genetic disorder with heterogeneous presentation, where acute encephalopathy is rarely described in literature. Therefore, initial neurologic symptoms could make the diagnosis and treatment challenging.
Case Presentation: A four-month-old male infant presented with acute encephalopathy, vomiting, bulging fontanel, decreased appetite and failure to thrive.
Radiographics
December 2024
From the Departments of Radiology (R.P., J.R.T., L.S., A.K.) and Pathology (D.B.B.), Stanford University, 300 Pasteur Dr, Palo Alto, CA 94304.
Acute cholecystitis is an inflammatory condition of the gallbladder typically incited by mechanical obstruction. Accurate diagnosis of this common clinical condition is challenging due to variable imaging appearances as well as overlapping clinical manifestations with biliary colic, acute hepatitis, pancreatitis, and cholangiopathies. In acute cholecystitis, increased dilatation and high intraluminal pressures lead to gallbladder inflammation and may progress to gangrenous changes, focal wall necrosis, and subsequent perforation.
View Article and Find Full Text PDFJPRAS Open
December 2024
Department of Plastic, Reconstructive- and Hand surgery, Amsterdam UMC, VU University Medical Center, Amsterdam, The Netherlands.
Background: Breast cancer is the most common cancer in women, and breast reconstruction improves the patient's quality of life. Autologous breast reconstruction provides benefits of natural appearance, feel, and long-term results without implant-associated problems. However, thin patients are not always suitable for standard autologous reconstructions.
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