Three different estrogen receptors (ERs) have been cloned and characterized in teleosts fish, i.e. ERalpha, ERbeta or ERbeta1 and ERgamma or ERbeta2. In order to study the sea bass ER subtype involved in the regulation of gonadotropin production, as well as to elucidate the possible involved neuronal pathways, we characterized the transactivation properties of the cloned sea bass ERalpha (sbERalpha) and studied its distribution in the brain and gonadotropic cells of the sea bass by in situ hybridization. The results revealed that sbERalpha transactivates promoters containing estradiol responsive elements (ERE) in a dose-response manner. The sbERalpha showed the highest affinity for 17-beta-estradiol. In situ hybridization studies demonstrated that ERalpha mRNA positive neurons are widely distributed within the sea bass brain, including the telencephalon, preoptic area, thalamus, hypothalamus, mesencephalic tectum and tegmentum and rhombencephalon. New estrogen dependent nuclei were described in all above areas. The sbERalpha was profusely expressed in the main neuroendocrine areas such as the preoptic area and hypothalamus, thus suggesting the steroidal modulation of the hypophysiotropic neurons. The presence of sbERalpha expression in the FSHbeta and LHbeta cells suggests a direct effect of estrogens in the control of gonadotropin hormone synthesis.
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http://dx.doi.org/10.1016/j.jchemneu.2007.05.010 | DOI Listing |
Animals (Basel)
January 2025
College of Marine Sciences, South China Agricultural University, Guangzhou 510642, China.
This research aimed to explore the impact of tea polyphenol (TP) supplementation on the development, antioxidant properties, immune responses, and gut wellness in largemouth bass (, LMB). Four diets with varying levels of TPs (0.00%, 0.
View Article and Find Full Text PDFAnimals (Basel)
January 2025
Institute of Fisheries, Guizhou Academy of Agricultural Sciences, Guiyang 550025, China.
The experiment was aimed at examining the influence of adding emodin to feeds on the growth performance, liver immunity, and resistance against infection among juvenile largemouth basses and other potential mechanisms. A total of 540 fish (45 ± 0.3 g) were randomly divided into 6 diets, including EM-0, EM-250, EM-500, EM-1000, EM-2000, and EM-4000 diets, in which 0, 250, 500, 1000, 2000, and 4000 mg kg emodin was added.
View Article and Find Full Text PDFAnimals (Basel)
January 2025
College of Fisheries, Southwest University, Chongqing 400715, China.
Largemouth bass (LMB, ), a commercially important farmed fish, is vulnerable to heat stress. Breeding heat-resistant LMB is highly desirable in the face of global warming. However, we still lack an efficient method to assess the heat resistance of LMB.
View Article and Find Full Text PDFAntioxidants (Basel)
January 2025
Wuxi Fisheries College, Nanjing Agricultural University, Wuxi 214081, China.
A seven-week trial was designed to evaluate the effects of dietary seaweed polysaccharide (SP) supplementation on the growth performance and physiological health of largemouth bass. The results reveal that the 0.05SP group showed the best growth performance.
View Article and Find Full Text PDFBMJ Paediatr Open
January 2025
Department of Paediatrics, Edward Francis Small Teaching Hospital, Banjul, Gambia
Background: Diarrhoea remains a leading cause of death in children. An intestinal adsorbent may reduce diarrhoea duration and severity.
Methods: Randomised controlled feasibility trial with two phases: phase 1 (0-4 hours and double-blind) and phase 2 (up to 5 days and open-label).
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