Objective: To review the development of nomograms and consortia efforts applying these tools to model outcome predictions associated with radical cystectomy.
Findings: Nomograms have been developed that provide individualized prediction of recurrence and survival following radical cystectomy, which provide significant improvement in predictive accuracy over tradition TNM staging.
Conclusions: Nomograms provide individualized risk assessment and outperform expert physician and conventional models used to predict outcome. Addition of biologic markers may improve predictive capability and improve the clinical utility of these valuable tools.
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http://dx.doi.org/10.1016/j.urolonc.2007.04.009 | DOI Listing |
Ned Tijdschr Geneeskd
January 2025
Integraal Kankercentrum Nederland (IKNL), Utrecht.
Unlabelled: The number of individuals with advanced cancer is increasing, making palliative care more important. However, there is limited knowledge in the Netherlands about the quality of care received by patients in the palliative phase. This is why the Netherlands comprehensive cancer organization (IKNL) started the 'eQuiPe study' to understand the experienced quality of care and quality of life of patients with advanced cancer and their relatives to further improve palliative care.
View Article and Find Full Text PDFComb Chem High Throughput Screen
January 2025
Baoying People's Hospital, Yangzhou 225800, China.
Shuanghuanglian (SHL) and its primary constituents have demonstrated protective effects against allergenic diseases. This review examines the anaphylactic and anti-allergenic activities of SHL and its constituents. We also discuss potential avenues for future research, particularly regarding the expansion of the clinical applications of SHL formulations (oral or nebulized) for the treatment of allergenic disorders.
View Article and Find Full Text PDFPsychiatr Hung
January 2025
Semmelweis Egyetem ÁOK Pszichiátriai és Pszichoterápiás Klinika, Budapest, Hungary, E-mail:
Autism spectrum disorder is a neurodevelopmental condition with unique characteristics of perception and neurocognition that begins in childhood and persists into adulthood. It significantly affects social integration and adaptation, and is a great challenge in terms of psychological coping. Intensive genetic and neurobiological research is focused at understanding the brain underpinnings of autism, and it is also at the forefront of pharmacological development.
View Article and Find Full Text PDFPsychiatr Hung
January 2025
Divisions of Pediatric Neurology and Genetics and Behavioral-Developmental Pediatrics, Department of Pediatrics, Faculty of Medicine, Necmettin Erbakan University, Meram, Konya, Türkiye, E-mail:
In this article, we discuss the use of bibliotherapy for depression in pediatric cancer patients, to attract attention to the importance of this method, overlooked by most health professionals. Cancer in children and adolescents is one of the most serious health problems worldwide. There is a subgroup of children with cancer at increased risk for anxiety and depression, and post-traumatic stress disorder.
View Article and Find Full Text PDFNeurol Neurochir Pol
January 2025
Department of Neurology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Katowice, Poland.
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS) that is usually diagnosed between the ages of 20 and 40. Changes in the immune system also observed in cancer may suggest a higher prevalence of cancer in the MS patient population. In recent years, many highly effective immunosuppressive drugs have been introduced into disease-modifying therapy (DMT) which may be associated with a higher risk of cancer development in patients with MS.
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