On the basis of studying of data on 1469 patients there is proposed a methodology of development of a system of automated diagnosis of osteo-chondrodysplasia in children. It is based on registration of the course peculiarities, variety of clinical and genetic forms, inter- and intragroup similarity and progredient course of diseases of the type. At the first stage there have been made a complex analysis of formalized clinico-roentgenologic signs of osteo-chondrodysplasia with the aid of "Rbase-5000" program package. Osteo-chondrodysplasia course regularities, revealed in this way, were used further on in the process of an expert system development for their automated diagnosis.
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