Background: Delays in seeking emergency care when experiencing serious symptoms may increase morbidity and mortality. Understanding the reasons for such delays may result in interventions to reduce them. We examined the relationship between ethnicity and the reluctance to use an emergency department (ED).
Methods: An exploratory multilingual telephone survey was completed in Greater Vancouver, British Columbia, with randomly selected men and women, aged 40 years and older, listed in the BC Ministry of Health Services Client Registry Database. Survey items included whether the respondents were "somewhat," "very" or "not" reluctant to use an ED. Reasons for reported degree of reluctance and potential correlates were explored including age, gender, income, education, anxiety, vulnerability, self-reported health status, life stress, and satisfaction with a previous ED visit. Multiple logistic regression analysis was conducted.
Results: Among 973 (56% response rate) participants (56.3% female) were 149 Chinese, 67 South Asian, 221 foreign-born (not Chinese or South Asian), and 536 Canadian-born participants (not Chinese or South Asian). Controlled for all potential confounders, Chinese (OR = 0.30, 95% CI = 0.19, 0.48) respondents were less likely than Canadian-born participants to report reluctance to use an ED. Anxiety (OR = 1.05, 95% CI = 1.02, 1.09) and dissatisfaction with a previous ED visit (OR = 1.85, 95% CI = 1.27, 2.68) were significant correlates.
Conclusions: Canadian-born participants may be at higher risk of delaying necessary treatment from EDs that have been publicized to have long waiting times. Further studies are needed to understand the role ethnicity plays in ED utilization.
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http://dx.doi.org/10.1007/BF03403717 | DOI Listing |
Phys Rev Lett
December 2024
CERN, Geneva, Switzerland.
High-energy nuclear collisions create a quark-gluon plasma, whose initial condition and subsequent expansion vary from event to event, impacting the distribution of the eventwise average transverse momentum [P([p_{T}])]. Disentangling the contributions from fluctuations in the nuclear overlap size (geometrical component) and other sources at a fixed size (intrinsic component) remains a challenge. This problem is addressed by measuring the mean, variance, and skewness of P([p_{T}]) in ^{208}Pb+^{208}Pb and ^{129}Xe+^{129}Xe collisions at sqrt[s_{NN}]=5.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
Institute of Physics, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
A search for violation of the charge-parity (CP) symmetry in the D^{+}→K^{-}K^{+}π^{+} decay is presented, with proton-proton collision data corresponding to an integrated luminosity of 5.4 fb^{-1}, collected at a center-of-mass energy of 13 TeV with the LHCb detector. A novel model-independent technique is used to compare the D^{+} and D^{-} phase-space distributions, with instrumental asymmetries subtracted using the D_{s}^{+}→K^{-}K^{+}π^{+} decay as a control channel.
View Article and Find Full Text PDFJ Med Internet Res
January 2025
Department of Nephrology, Hunan Key Laboratory of Kidney Disease and Blood Purification, The Second Xiangya Hospital of Central South University, Changsha, China.
Background: Acute kidney injury (AKI) is a common complication in hospitalized older patients, associated with increased morbidity, mortality, and health care costs. Major adverse kidney events within 30 days (MAKE30), a composite of death, new renal replacement therapy, or persistent renal dysfunction, has been recommended as a patient-centered endpoint for clinical trials involving AKI.
Objective: This study aimed to develop and validate a machine learning-based model to predict MAKE30 in hospitalized older patients with AKI.
Cancer Immunol Immunother
January 2025
Department of Respiratory and Critical Medicine, the First Affiliated Hospital of Soochow University, 899 Pinghai Road, Suzhou, 215006, China.
Despite identifying specific CD8 T cell subsets associated with immunotherapy resistance, the molecular pathways driving this process remain elusive. Given the potential role of CD38 in regulating CD8 T cell function, we aimed to investigate the accumulation of CD38CD8 T cells in lung cancer and explore its role in immunotherapy resistance. Phenotypic analysis of tumoral CD8 T cells from both lung cancer patients and immunotherapy-resistant preclinical models revealed that CD38-expressing CD8 T cells consist of CD38 and CD38 subsets.
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