The SP/KLF transcription factor family contains over 25 members sharing a DNA-binding domain composed of three zinc fingers of the C(2)H(2) type. We previously identified the sixth member of the SP subfamily (Sp6). The 5' end of the Sp6 transcript was not cloned and was predicted bioinformatically. A mouse molar tooth cDNA was then isolated differing from the Sp6 sequence by its 5' end, and was named epiprofin. Sp6 and epiprofin are currently used as synonyms. Here, we show that the Sp6 transcript possesses a first exon distinct from the epiprofin one: the Sp6 gene thus uses two promoters, generating two transcript variants which differ in their first exon. Furthermore, we identified an Sp6 opposite strand transcript (Sp6os) and examined, by quantitative RT-PCR experiments, the presence and the abundance of these two transcripts in mouse tissues. We also mapped the mouse locus by FISH to chromosome 11D.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.biochi.2007.05.011 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Identifying human activities causing water pollution based on microbial community sequencing and source classifier machine learning.
Environ Int
December 2024
State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Science, Beijing 100012, China; State Environmental Protection Key Laboratory of Estuarine and Coastal Environment, Chinese Research Academy of Environmental Science, Beijing 100012, China; State Key Laboratory of Pollution Control and Resource Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai, 200092, China. Electronic address:
Identifying and differentiating human activities is crucial for effectively preventing the threats posed by environmental pollution to aquatic ecosystems and human health. Machine learning (ML) is a powerful analytical tool for tracking human impacts on river ecosystems based on high-through datasets. This study employed an ML framework and 16S rRNA sequencing data to reveal microbial dynamics and trace human activities across China.
View Article and Find Full Text PDFEffects of acupressure on pain and first mobilisation distance after caesarean section: A double-blind randomised controlled study.
Explore (NY)
December 2024
Department of Obstetrics and Gynaecology, Department of Gynaecological Oncology, Mersin University, Mersin, Türkiye.
Background: Postoperative pain is one of the most common problems after caesarean section (CS). Pain reduction and effective mobilisation after CS positively affect maternal and infant health.
Aim: This study aimed to determine the effects of acupressure applied to women after CS on pain intensity and first mobilisation distance.
Acupressure as an Effective Method for Improving Sexual Function in Depressant Women Treated with Selective Serotonin Reuptake Inhibitor: a Randomized Clinical Trial.
J Acupunct Meridian Stud
December 2024
Medicinal Plants Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.
Importance: Sexual dysfunction in individuals suffering from depression may be both a symptom of the disorder and a side effect of antidepressants. To date, and to our knowledge, no randomized controlled trials have demonstrated the effectiveness of acupressure on sexual function in women of reproductive age who take antidepressants.
Objective: This study aims to evaluate the effect of acupressure on sexual function in women of reproductive age taking Selective Serotonin Reuptake inhibitors (SSRIs).
[Effect of percutaneous acupoint electrical stimulation on immune function and postoperative recovery in patients with total knee arthroplasty].
Zhongguo Gu Shang
December 2024
Department of Anesthesiology, Gansu Provincial Hospital of TCM, Lanzhou 730000, Gansu, China.
Objective: To evaluate clinical effect of transcutaneous acupoint electrical stimlation (TEAS) on perioperative immune function and postoperative recovery in patients with total knee arthroplasty (TKA).
Methods: From November 2021 to July 2022, 80 patients with unilateral TKA were selected and divided into TEAS group and sham TEAS group according to different treatment methods. There were 40 patients in TEAS group, including 9 males and 31 females;aged from 61 to 79 years old with an average of (66.
Objectives: To analyze the regularity of acupoint selection and compatibility of acupuncture and moxibustion for Parkinson's disease (PD) using complex network analysis technology, so as to provide the basis and treatment strategies for clinical acupuncture and moxibustion treatment of PD.
Methods: Relevant literature published in databases of China National Knowledge Infrastructure (CNKI), Wanfang, VIP, PubMed, and Web of Science from the inception to December of 2023 was retrieved. The literature was screened based on inclusion and exclusion criteria to establish a prescription database for acupuncture treatment of PD.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!