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Exploring the relationship between upwelling intensity and socio-ecological attributes of marine exploitation areas for benthic resources (MEABRs), along the southern Humboldt Current system.
J Environ Manage
February 2025
Departamento de Ecología y Biodiversidad, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, Chile; Centro de Investigaciones Marinas de Quintay, Universidad Andres Bello, Chile. Electronic address:
The Eastern Boundary Upwelling Systems (EBUS) sustains some of the most productive marine systems on Earth. Within each of these systems, the upwelling process exhibits spatial and temporal variation resulting in marked differences in upwelling intensity and seasonality along extensive coastlines. The study of this variation is well needed, given the magnitude of the services provided by upwelling, and the impending impacts of global warming on EBUS.
View Article and Find Full Text PDFMass Spectrometry-Based Protein Footprinting for Protein Structure Characterization.
Acc Chem Res
January 2025
Department of Chemistry, Washington University, St. Louis, Missouri 63130, United States.
ConspectusProtein higher-order structure (HOS) is key to biological function because the mechanisms of protein machinery are encoded in protein three-dimensional structures. Mass spectrometry (MS)-based protein footprinting is advancing protein structure characterization by mapping solvent-accessible regions of proteins and changes in H-bonding, thereby providing higher order structural information. Footprinting provides insights into protein dynamics, conformational changes, and interactions, and when conducted in a differential way, can readily reveal those regions that undergo conformational change in response to perturbations such as ligand binding, mutation, thermal stress, or aggregation.
View Article and Find Full Text PDFExpectations and experiences of pain during medical abortion at home: a secondary, mixed-methods analysis of a patient survey in England and Wales.
BMJ Sex Reprod Health
December 2024
Centre for Reproductive Research & Communication, British Pregnancy Advisory Service, London, UK.
Objective: To explore experiences of pain during medical abortion and provide patient-centred recommendations for improving abortion experience and pain counselling.
Methods: We invited patients of British Pregnancy Advisory Service who underwent medical abortion up to 10 weeks' gestation to participate in an online, English language questionnaire from November 2021 to March 2022. Participants answered questions about pain, method preference, abortion experience, advice, and how they would describe pain experienced to a friend.
Shifting agricultural land use and its unintended water consumption in the North China Plain.
Sci Bull (Beijing)
December 2024
Bureau of Economic Geology, Jackson School of Geosciences, University of Texas at Austin, Austin TX, 78712, USA.
Agricultural land use (ALU) critically influences food production and water resource allocation. This study examines the dynamics of ALU in the North China Plain (NCP), a region characterized by intensive agriculture and severe groundwater over-exploitation, focusing on the multidimensional drivers and their implications for water resource management. By employing an elaborate classification scheme based on satellite imagery and extensive first-hand field data, we identified significant shifts in crop patterns.
View Article and Find Full Text PDFThe three-domain impact framework for characterizing impact of patient involvement in health technology assessment.
Int J Technol Assess Health Care
November 2024
Patient Voice Initiative, Sydney, Australia.
Objectives: Evaluating the impact of patient involvement in health technology assessments (HTA) may help improve practices and avoid ineffective activities. Evaluation, however, continues to be infrequent, inconsistent, and often only relates to process quantity or quality. The Patient and Citizen Involvement in HTA Interest Group (PCIG) within Health Technology Assessment International set out to contextualize this impact to support evaluation.
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