We present an algorithm for estimating the color demixing matrix based on the color fringe patterns captured from the reference plane or the surface of the object. The advantage of this algorithm is that it is a blind approach to calculating the demixing matrix in the sense that no extra images are required for color calibration before performing profile measurement. Simulation and experimental results convince us that the proposed algorithm can significantly reduce the influence of the color cross talk and at the same time improve the measurement accuracy of the color-channel-based phase-shifting profilometry.
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http://dx.doi.org/10.1364/josaa.24.002372 | DOI Listing |
Nat Commun
July 2024
Laboratoire Kastler Brossel, ENS-Université PSL, CNRS, Sorbonne Université, Collège de France, 24 Rue Lhomond, Paris, F-75005, France.
Optical methods based on thin multimode fibers (MMFs) are promising tools for measuring neuronal activity in deep brain regions of freely moving mice thanks to their small diameter. However, current methods are limited: while fiber photometry provides only ensemble activity, imaging techniques using of long multimode fibers are very sensitive to bending and have not been applied to unrestrained rodents yet. Here, we demonstrate the fundamentals of a new approach using a short MMF coupled to a miniscope.
View Article and Find Full Text PDFAPL Bioeng
September 2024
Benjamin Levich Institute and Physics Department, City College of New York, New York, New York 10031, USA.
Breast cancer invasion into adipose tissue strongly influences disease progression and metastasis. The degree of cancer cell invasion into adipose tissue depends on both biochemical signaling and the mechanical properties of cancer cells, adipocytes, and other key components of adipose tissue. We model breast cancer invasion into adipose tissue using discrete element method simulations of active, cohesive spherical particles (cancer cells) invading into confluent packings of deformable polyhedra (adipocytes).
View Article and Find Full Text PDFBull Math Biol
April 2024
Department of Mathematics, Florida State University, Tallahassee, FL, USA.
Liquid-liquid phase separation is an intracellular mechanism by which molecules, usually proteins and RNAs, interact and then rapidly demix from the surrounding matrix to form membrane-less compartments necessary for cellular function. Occurring in both the cytoplasm and the nucleus, properties of the resulting droplets depend on a variety of characteristics specific to the molecules involved, such as valency, density, and diffusion within the crowded environment. Capturing these complexities in a biologically relevant model is difficult.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
June 2024
School of Physics, Chemistry and Earth Sciences, University of Adelaide, Adelaide, South Australia, 5005, Australia.
ArXiv
March 2024
Department of Mechanical Engineering & Materials Science, Yale University, New Haven, Connecticut 06520.
Breast cancer invasion into adipose tissue strongly influences disease progression and metastasis. The degree of cancer cell invasion into adipose tissue depends on numerous biochemical and physical properties of cancer cells, adipocytes, and other key components of adipose tissue. We model breast cancer invasion into adipose tissue as a physical process by carrying out simulations of active, cohesive spherical particles (cancer cells) invading into confluent packings of deformable polyhedra (adipocytes).
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