Severity: Warning
Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 143
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 143
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 209
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3098
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Severity: Warning
Message: Attempt to read property "Count" on bool
Filename: helpers/my_audit_helper.php
Line Number: 3100
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3100
Function: _error_handler
File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Purpose Of Review: Venom skin tests constitute the cornerstone in establishing the diagnosis of venom allergy. In spite of their fundamental role, data regarding their reproducibility and variability are rather sparse. This paper is an overview of our current knowledge on the extent of variability in venom skin testing, the possible causes for this phenomenon and its clinical implications. It points out certain clinical situations in which this possible variability should be taken into account and anticipates potential venues of expanding our understanding of this debatable subject.
Recent Findings: A single recent study addressed the reproducibility of skin tests and serum venom-specific immunoglobulin E levels. Using a simple positive-negative or vice versa criterion for all three venoms examined on two different sessions, this study showed an overall 66% reproducibility of the skin test reactions and 59% reproducibility of the venom-specific immunoglobulin E assay results. According to an accompanying editorial, however, the validity of these results needs to be confirmed.
Summary: Determination of the real magnitude of venom skin test variability is required. At present, in specific clinical situations, repeated skin tests and measurement of serum venom-specific immunoglobulin E should be considered before the initiation of venom immunotherapy.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1097/ACI.0b013e3281f828f8 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!