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Impact of Dipyrone Administration on Postoperative Analgesia and Aspirin Effect in Patients Undergoing Coronary Artery Bypass Grafting: The Prospective Randomized DipASA Study.
J Cardiothorac Vasc Anesth
January 2025
Department of Anesthesiology, University Medical Center Regensburg, Regensburg, Germany. Electronic address:
Objective: The aim of the study was to investigate the impact of dipyrone administration on postoperative analgesia and acetylsalicylic acid (ASA) effect in patients undergoing coronary artery bypass grafting (CABG).
Design: A prospective randomized study.
Setting: Single-university hospital setting.
Dataset for discovering new hypertension small molecules using machine learning-aided computational fragment-based design.
Data Brief
August 2024
Institute for Intelligent Systems, University of Johannesburg, 69 Kingsway Avenue, Auckland Park, Johannesburg 2092, Gauteng Province, South Africa.
This dataset demonstrates the use of computational fragmentation-based and machine learning-aided drug discovery to generate new lead molecules for the treatment of hypertension. Specifically, the focus is on agents targeting the renin-angiotensin-aldosterone system (RAAS), commonly classified as Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin II Receptor Blockers (ARBs). The preliminary dataset was a target-specific, user-generated fragment library of 63 molecular fragments of the 26 approved ACEI and ARB molecules obtained from the ChEMBL and DrugBank molecular databases.
View Article and Find Full Text PDFEnhancing COVID-19 Risk Mitigation in Bisha City Primary Schools: Investigating Teacher and Administrative Staff Awareness Through a Comprehensive Survey.
Cureus
May 2024
College of Medicine, University of Bisha, Bisha, SAU.
Background and aims This research investigates COVID-19 awareness among primary school teachers and staff in Bisha City. It aims to enhance safety protocols by examining knowledge, awareness levels, and demographic associations. Despite school reopening, concerns linger.
View Article and Find Full Text PDFResponse Rates by Condom Use Measurement Type Among Sexually Active Young Black Men Who Have Sex With Women.
Sex Transm Dis
November 2024
From Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA.
Background: Measuring condom use accurately is important to understanding sexual behaviors; however, there is still no consensus on the criterion standard of condom use measurement. In this study, authors aimed to investigate if nonresponse rates were higher when absolute or relative frequency condom use questions were used.
Methods: This study used Check It study data of Black men who have sex with women aged 15 to 26 years in New Orleans, LA.
Exploring Patients' Perceptions on Injectable Opioid Agonist Treatment: Influences on Treatment Initiation and Implications for Practice.
Eur Addict Res
February 2024
Department of Psychiatry and Psychotherapy, Clinic for Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Berlin, Germany.
Introduction: Injectable opioid agonist treatment (iOAT) with diacetylmorphine is an effective option for individuals previously considered non-responsive to opioid substitution treatment. Despite implementation in Canada and several European countries, relatively few eligible people choose to initiate iOAT. To better understand what encourages or deters prospective patients from initiating iOAT, the current study explores patients' perceptions on iOAT and how these influence therapy initiation in practice.
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