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Efficacy of lactoferrin supplementation in pediatric infections: A systematic review and meta-analysis.
Biochem Cell Biol
January 2025
Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt, Lima, Lima, Peru.
Pediatric infections account for approximately one-third of all deaths in children under 5 globally. Lactoferrin (LF) supplementation has the potential to reduce infection-related morbidity due to its antimicrobial, anti-inflammatory and immunoregulatory properties. We conducted a systematic review and meta-analysis of oral LF supplementation randomized controlled trials (RCT) in population under 18 years old.
View Article and Find Full Text PDFClinical Characteristics of Hospitalized Children With Coronavirus Disease 2019 After the Spread of the BA.5 Omicron Variants in Japan.
Pediatr Infect Dis J
January 2025
From the Department of Pediatrics, Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan.
Background: The spread of the BA.5 Omicron variant of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has increased the number of hospitalized children. However, the impact of the spread of new omicron subvariants in children remains poorly described.
View Article and Find Full Text PDFA 4-year follow-up of the need for orthodontic treatment using the Dental Aesthetic Index-DAI: an exploratory analysis.
Braz Oral Res
January 2025
Universidade Estadual de Campinas - Unicamp, Piracicaba Dental School, Department of Health Sciences and Child Dentistry, Piracicaba, SP, Brazil.
This study aim was to evaluate the need for orthodontic treatment of mixed to permanent dentition using the Dental Aesthetic Index (DAI) in a 4-year follow-up. A longitudinal study was conducted with 353 children in the stages from mixed (T1) to permanent (T2) dentition. The need for orthodontic treatment was assessed using the DAI categorized into: DAI 1 (absence of malocclusion and orthodontic treatment need; DAI ≤ 25); DAI 2 (malocclusion is defined and elective orthodontic treatment is needed; DAI = 26 to 30); DAI 3 (severe malocclusion and a desirable orthodontic treatment need; DAI = 31 to 35) and DAI 4 (severe malocclusion and a mandatory orthodontic treatment need; DAI ≥ 36).
View Article and Find Full Text PDFThe effects of a brief intervention at home based on shared reading to promote children's oral language.
Codas
January 2025
Centro de Matemática, Computação e Cognição, Universidade Federal do ABC - UFABC - Santo André (SP), Brasil.
Purpose: The general aim of the present study was to analyse eight mother-child interactions during shared reading with children and to assess the efficacy of a brief intervention with the mothers to promote changes in the strategies they used to develop their children's oral language. The specific objectives were to work collaboratively with mothers, to analyse the interactions between mothers and their children before and at the end of the intervention period.
Methods: Mothers participated in five meetings to reflect collaboratively on strategies to promote improvements in communicative interactions in a family context and in children's oral language and during the shared reading episodes.
Reconstructing prehistoric lifeways using multi-Isotope analyses of human enamel, dentine, and bone from Legaire Sur, Spain.
PLoS One
January 2025
Archaeology, Environmental Changes and Geo-Chemistry, Vrije Universiteit Brussel, Belgium.
Megalithism has been repetitively tied to specialised herding economies in Iberia, particularly in the mountainous areas of the Basque Country. Legaire Sur, in the uplands of Álava region, is a recently excavated passage tomb (megalithic monument) that held a minimum number of 25 individuals. This study analysed the carbon, nitrogen, oxygen, and strontium isotope ratios of 18 individuals, in a multi-tissue sampling study (successional tooth enamel sampling, incremental dentine sampling, and bulk bone collagen sampling).
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