Sleep disturbances and impaired daytime functioning in outpatients with newly diagnosed lung cancer.

Background: Clinical experience suggests that lung cancer (LC) is associated with sleep disturbances that may contribute to impaired daytime functioning and quality of life. Using questionnaires and home actigraphic recordings, we tried to determine whether sleep quality and daytime alertness are impaired in patients with newly diagnosed LC.

Patients And Methods: Twenty-nine outpatients with newly diagnosed LC and an Eastern Cooperative Oncology Group performance status
Results: LC patients had higher PSQI (9.6+/-3.7 versus 5.6+/-3.2; p<0.001) and higher ESS (8.6+/-3.7 versus 5.6+/-3.2; p=0.01) than NC patients indicating worse quality of sleep and more excessive daytime sleepiness. Both physical and mental components score of SF-36 were lower in LC patients (p<0.001) indicating lower quality of life. Wrist actigraphy data showed significantly lower sleep efficiency and a higher sleep fragmentation during the night and lower mean activity during the day in LC patients.

Conclusions: Patients with newly diagnosed LC and performance status

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http://dx.doi.org/10.1016/j.lungcan.2007.05.021	DOI Listing