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Mechanosensitive ion channels in glaucoma pathophysiology.
Vision Res
October 2024
Spencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA. Electronic address:
Force sensing is a fundamental ability that allows cells and organisms to interact with their physical environment. The eye is constantly subjected to mechanical forces such as blinking and eye movements. Furthermore, elevated intraocular pressure (IOP) can cause mechanical strain at the optic nerve head, resulting in retinal ganglion cell death (RGC) in glaucoma.
View Article and Find Full Text PDFPrevalence of dry eye in people over 50 years old in Beichen district, Tianjin city: a cross-sectional population-based survey.
BMC Public Health
August 2024
Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.
Background: A cross-sectional population-based survey in the Beichen district of Tianjin was conducted to estimate the prevalence of dry eye disease (DED) among the population over 50 years old with Dry Eye Workshop (DEWS) II and Chinese expert consensus (CEC) criteria.
Methods: A total of 5791 subjects over 50 years old were enrolled. Ocular surface disease index (OSDI) questionnaire, lipid layer thickness (LLT), partial blink ratio (PBR), fluorescein tear film breakup time (FBUT), Schirmer I test (SIT), fluorescein staining, meibomian gland dropout, meibomian gland expression scores (MES) and quantity scores (MQS) was assessed.
Large corneal epithelial detachment as a complication of wound burping to release aqueous humor for elevated intraocular pressure following cataract surgery.
J Surg Case Rep
June 2024
Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore 308232, Singapore.
Article Synopsis
- Wound burping is a technique used to quickly lower intraocular pressure after cataract surgery, especially when spikes occur soon post-operation.
- A 55-year-old man experienced complications, including elevated intraocular pressure and corneal issues, following his surgery 20 days earlier, leading to the need for the burping technique.
- The procedure resulted in an epithelial bulla that burst and caused a complete sloughing off of the corneal epithelium, which eventually healed over 10 days, highlighting that wound burping can have significant risks, including epithelial detachment.
Investigating the Blink Reflex Abnormality in Dry Eye Patients.
Cureus
November 2023
Neurology Department, Pamukkale University, Denizli, TUR.
Introduction Dry eye is an ocular surface disorder caused by increased evaporation, decreased tear production, or mixed form. Tears are secreted by the lacrimal gland after lacrimal nerve stimulation connected to the facial nerve. In nerve damage, tear secretion decreases, and dry eye develops.
View Article and Find Full Text PDFOcular Surface Changes in Primary Open Angle Glaucoma Patients Treated With Topical Antihypertensive Drugs.
J Glaucoma
October 2023
Department of Ophthalmology, Centro Hospitalar Universitário de Santo António.
Prcis: In this study, patients with glaucoma undergoing topical antihypertensive (TAH) drugs had changes in the ocular surface and more dry eye symptoms than controls. Clinicians should recognize the influence of TAH drops on exacerbating ocular surface disease.
Purpose: The purpose of this study was to evaluate the ocular surface of eyes with glaucoma treated with TAH drugs.
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