Recent research has produced disagreement about the usage and usefulness of external memory aids across age groups. The present study examined the use and perceived usefulness of commercial memory aids as a function of the ages of users and potential users. Three age groups (ages 20, 45 and 65 years) were asked to indicate whether they owned each of thirty different commercial aids and regardless of ownership, to rate the degree of usefulness of each of the aids. Each age group used certain aids or perceived certain aids as more useful, than did other age groups. The pattern of results suggest that memory aid usage differs with age partly because the memory tasks required of a person change with life stage.
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http://dx.doi.org/10.2190/0J3N-F3QB-TEDH-CUYX | DOI Listing |
bioRxiv
January 2025
Aaron Diamond AIDS Research Center, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, USA.
Although emerging data have revealed the critical role of memory CD8 T cells in preventing and controlling SARS-CoV-2 infection, virus-specific CD8 T-cell responses against SARS-CoV-2 and its memory and innate-like subsets in unvaccinated COVID-19 patients with various disease manifestations in an HLA-restricted fashion remain to be understood. Here, we show the strong association of protective cellular immunity with mild COVID-19 and unique cell types against SARS-CoV-2 virus in an HLA-A2 restricted manner. ELISpot assays reveal that SARS-CoV-2-specific CD8 T-cell responses in mild COVID-19 patients are significantly higher than in severe patients, whereas neutralizing antibody responses against SARS-CoV-2 virus significantly correlate with disease severity.
View Article and Find Full Text PDFSensors (Basel)
January 2025
School of Information Science and Technology, Southwest Jiaotong University, Chengdu 611756, China.
Real-time and accurate traffic forecasting aids in traffic planning and design and helps to alleviate congestion. Addressing the negative impacts of partial data loss in traffic forecasting, and the challenge of simultaneously capturing short-term fluctuations and long-term trends, this paper presents a traffic forecasting model, D-MGDCN-CLSTM, based on Multi-Graph Gated Dilated Convolution and Conv-LSTM. The model uses the DTWN algorithm to fill in missing data.
View Article and Find Full Text PDFSci Rep
January 2025
Institute for Anthropological Research, 10000, Zagreb, Croatia.
Modelling of pollutants provides valuable insights into air quality dynamics, aiding exposure assessment where direct measurements are not viable. Machine learning (ML) models can be employed to explore such dynamics, including the prediction of air pollution concentrations, yet demanding extensive training data. To address this, techniques like transfer learning (TL) leverage knowledge from a model trained on a rich dataset to enhance one trained on a sparse dataset, provided there are similarities in data distribution.
View Article and Find Full Text PDFAIDS Care
January 2025
South African Medical Research Council / Stellenbosch University Genomics of Brain Disorders Research Unit, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa.
HIV and the consequences of HIV-associated neurocognitive disorders (HAND) disproportionally affect South African women. Longitudinal neurocognitive data on women with HIV are limited. We tracked longitudinal neurocognitive profiles of South African women with HIV (baseline = 140) compared to women without HIV (baseline = 156).
View Article and Find Full Text PDFAge Ageing
January 2025
Division of Psychiatry, University College London, London, UK.
Background: Age-related hearing loss and mild cognitive impairment (MCI) independently increase dementia risk. The Ageing and Cognitive Health Evaluation in Elders randomised controlled trial (RCT) found hearing aids reduce cognitive decline in high-risk older adults with poor hearing.
Methods: This pilot RCT in London memory clinics randomised people with MCI (aged ≥55, untreated hearing loss defined as Pure Tone Average 0.
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