Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2144/000112496 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Development of a Single-Molecule Biosensor Based on Polymerization-Transcription-Mediated Target Regeneration for Simultaneously One-Pot Detection of Multiple piRNAs.
Anal Chem
January 2025
School of Chemistry and Chemical Engineering, State Key Laboratory of Digital Medical Engineering, Southeast University, Nanjing 211189, China.
PIWI-interacting RNAs (piRNAs) are a class of small noncoding RNAs associated with PIWI proteins within the male germline, and they play significant roles in maintaining genome stability via the modulation of gene expression. The piRNAs are implicated in the progression of various cancers, but the simultaneous monitoring of multiple piRNAs remains a challenge. Herein, we construct a single-molecule biosensor based on polymerization-transcription-mediated target regeneration for the simultaneous one-pot detection of multiple piRNAs.
View Article and Find Full Text PDFLogical Analysis of Multiple miRNAs with Isothermal Molecular Classifiers Based on LATE-RCA.
Nano Lett
January 2025
Key Laboratory of Clinical Laboratory Diagnostics (Chinese Ministry of Education), College of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, P. R. China.
Logical analysis of multiple-miRNA expression information and immediate output of diagnostic results facilitates early cancer detection. In this work, we constructed an isothermal molecular classifier capable of performing computations on multiple miRNAs and directly providing diagnosis results. First, we developed linear-after-the-exponential rolling circle amplification (LATE-RCA), a nearly linear isothermal amplification that does not destroy the original quantitative information about miRNAs.
View Article and Find Full Text PDFPrevalence of Post-Traumatic Stress Disorder and Associated Factors Among Internally Displaced Persons (IDPS) In Mogadishu Cross-Sectional Study.
Psychol Res Behav Manag
January 2025
Department of Public Health, Federal Ministry of Health and Human Services, Mogadishu, Somalia.
Background: An important mental health concern is Post-Traumatic Stress Disorder (PTSD), especially for Internally Displaced Persons (IDPs) in the Horn of Africa. Limited access to psychosocial support and primary health care exacerbates mental health issues.
Aim: This study was to examine the prevalence of post-traumatic stress disorder and factors associated with IDPs in Mogadishu.
High-Security Data Encryption Enabled by DNA Multi-Strand Solid-Phase Hybridization and Displacement in Inkjet-Printed Microarrays.
ACS Appl Mater Interfaces
January 2025
Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China.
Multicolor fluorescent encryption systems that respond to specific stimuli have drawn widespread attention to data storage and encryption due to their low cost and facile data access. However, existing encryption systems are limited by encryption materials, restricting their encryption depth. This study uses DNA molecules as encryption materials that offer exceptional specificity and encryption depth within sequences.
View Article and Find Full Text PDFCholera in Nigeria: A review of outbreaks, trends, contributing factors, and public health responses.
Niger Med J
January 2025
Department of Medical Laboratory Services, Federal Medical Center, Yenagoa, Bayelsa State, Nigeria.
Cholera remains a significant public health challenge in Nigeria, with recurrent outbreaks exacerbated by inadequate water, sanitation, and hygiene (WASH) infrastructure, as well as conflict and displacement. This review examines cholera outbreaks in Nigeria from 2010 to 2024, analyzing epidemiological trends, contributing factors, and public health responses. Seasonal peaks during periods of heavy rainfall and flooding have consistently facilitated transmission, with Northern regions disproportionately affected due to poor infrastructure and ongoing conflicts.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!