The aim of the present paper was to examine the organization of story memory in schizophrenia. Participants were 35 patients with schizophrenia and 24 healthy subjects who completed the Wechsler Memory Scale-Revised. The organization of story memory was evaluated with the Logical Memory subtest. Schizophrenia patients scored significantly lower than controls on thematic sequencing, and significant negative correlations were found between positive symptoms and thematic sequencing. These findings suggest that schizophrenia has deficits in organization of story memory, which are related to symptoms such as disorganized thoughts and behavior.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1111/j.1440-1819.2007.01675.x | DOI Listing |
Cell Rep
January 2025
Centre for Systems Neuroscience, University of Leicester, Leicester, UK; Hospital Del Mar Medical Research Institute (IMIM), Barcelona, Spain; Institució Catalana de Recerca I Estudis Avançats (ICREA), Barcelona, Spain; Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:
In subjects implanted with intracranial electrodes, we use two different stories involving the same person (or place) to evaluate whether and to what extent context modulates human single-neuron responses. Nearly all neurons (97% during encoding and 100% during recall) initially responding to a person/place do not modulate their response with context. Likewise, nearly none (<1%) of the initially non-responsive neurons show conjunctive coding, responding to particular persons/places in a particular context during the tasks.
View Article and Find Full Text PDFNeurology
January 2025
Leonard Davis School of Gerontology, University of Southern California, Los Angeles.
Background And Objectives: Cerebrovascular reactivity (CVR) represents the ability of cerebral blood vessels to regulate blood flow in response to vasoactive stimuli and is related to cognition in cerebrovascular and neurodegenerative conditions. However, few studies have examined CVR in the medial temporal lobe, known to be affected early in Alzheimer disease and to influence memory function. We aimed to examine whether medial temporal CVR is associated with memory function in older adults with and without mild cognitive impairment (MCI).
View Article and Find Full Text PDFBrain Sci
November 2024
Department of Health Sciences, University of Florence, 50121 Florence, Italy.
Background: Borderline Personality Disorder (BPD) is a prevalent psychopathological condition, affecting 0.7-2.7% of the general population.
View Article and Find Full Text PDFBrain Lang
January 2025
Center for Childhood Deafness, Language, and Learning, Boys Town National Research Hospital, Omaha, NE.
Developmental Language Disorder (DLD) is a common neurodevelopmental condition characterized by significant difficulty with language learning, comprehension, and expression. The neurocognitive bases of DLD are underspecified but are thought to be related, in part, to altered basal ganglia (BG). The BG are known to have a high level of brain iron, which contributes to myelination and dopaminergic pathways among other physiological mechanisms.
View Article and Find Full Text PDFHippocampus
January 2025
Department of Neurobiology and Biophysics, University of Washington School of Medicine, Washington National Primate Research Center, Seattle, Washington, USA.
During the 1990s and early 2000s, research in humans and in the nonhuman primate model of human amnesia revealed that tasks involving free viewing of images provided an exceptionally sensitive measure of recognition memory. Performance on these tasks was sensitive to damage restricted to the hippocampus as well as to damage that included medial temporal lobe cortices. Early work in my laboratory used free-viewing tasks to assess the neurophysiological correlates of recognition memory, and the use of naturalistic visual exploration opened rich avenues to assess other aspects of the impact of eye movements on neural activity in the hippocampus and entorhinal cortex.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!