Purpose: Pilonidal sinus disease is usually located in the sacrococcygeal region. Verrucous carcinoma (Buschke-Lowenstein) is a rare variant of squamous cell carcinoma with distinct clinical and histopathologic features, with a favorable prognosis. Malignant degeneration is an infrequent complication, which is associated with a high recurrence rate and poor prognosis.

Materials And Methods: A case report is presented.

Results: We report a 48-year-old man with a 10-year history of recurrent pilonidal sinus disease presented with a sacrococcygeal verrucous carcinoma arising in the pilonidal sinus tract and associated with good prognosis. After operation, a 5-year disease-free follow-up was observed.

Conclusion: Careful inspection of the pilonidal area in all chronic and long-standing inflammatory processes is important and should be evaluated for malignant transformation.

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Source
http://dx.doi.org/10.1007/s00423-007-0209-yDOI Listing

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