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Possible viral agents to consider in the differential diagnosis of blepharoconjunctivitis.
World J Virol
December 2024
Department of Ophthalmology, University Hospital of Udine, Udine 33100, Italy.
Background: Blepharoconjunctivitis poses a diagnostic challenge due to its diverse etiology, including viral infections. Blepharoconjunctivits can be acute or chronic, self-limiting, or needing medical therapy.
Aim: To review possible viral agents crucial for accurate differential diagnosis in cases of blepharoconjunctivitis.
Dupilumab-Associated Bilateral Conjunctival Papillomas and Corneal Perforation.
Cornea
November 2024
Royal Victorian Eye and Ear Hospital, East Melbourne, Australia.
Purpose: We report a unique case of significant human papillomavirus-associated conjunctival papillomas and severe corneal ulceration leading to corneal perforation in a patient treated with dupilumab for atopic dermatitis.
Methods: This study is a case report and literature review of severe corneal side effects related to dupilumab.
Results: A 27-year-old man with severe atopic dermatitis and no ocular history was administered dupilumab 300 mg via subcutaneous injections every 2 weeks with an excellent response.
Corneal Ectasia Following Cosmetic Keratopigmentation.
Cornea
November 2024
Cornea and Refractive Surgery Department, Vissum (Miranza Group), Alicante, Spain; and.
Article Synopsis
- This study details 5 patients (10 eyes) who experienced corneal ectasia after undergoing cosmetic keratopigmentation (KTP) using a femtosecond laser.
- The research observed progressive changes in corneal shape and vision over 6 months to 4 years post-surgery, despite all patients initially having normal corneal conditions.
- The findings highlight that corneal ectasia can occur as a complication of KTP, emphasizing the need for thorough preoperative evaluations and patient education on avoiding eye rubbing to mitigate risks.
Scrotal and penile edema in a patient with incomplete kawasaki disease: a case report and brief literature review.
BMC Pediatr
October 2024
Department of Pediatric Infectious Disease, Children's Hospital of Michigan, 3901 Beaubien Blvd, Detroit, MI, 48201, USA.
Article Synopsis
- Kawasaki disease (KD) is a vasculitis that mainly impacts children under 5 and can lead to serious heart issues if not treated quickly with IVIG and aspirin.
- A unique case of incomplete Kawasaki disease is reported in a 2-year-old boy who experienced fever, conjunctivitis, and significant scrotal and penile edema.
- This case highlights the importance of recognizing genitourinary symptoms in KD for timely diagnosis and treatment, marking the first noted instance of penile edema in KD literature.
A Randomized, Multicenter Phase 3 Clinical Trial Evaluating Intracanalicular Dexamethasone Insert for the Treatment of Allergic Conjunctivitis.
Clin Ophthalmol
September 2024
Ocular Therapeutix, Inc., Bedford, MA, USA.
Article Synopsis
- A study was conducted to evaluate the effectiveness and safety of a dexamethasone intracanalicular insert (DEX) for treating allergic conjunctivitis (AC) in adults, comparing it to a placebo.
- 96 participants were randomized into two groups (DEX and placebo) and underwent allergen challenges to assess symptoms like ocular itching and redness over 30 days.
- Results showed that the DEX insert significantly reduced eye itching and redness compared to placebo without serious side effects, indicating it might be a safe and effective treatment option for AC.
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