We report an 18-year old patient with hypochromic anaemia and subfebriles states and long-persisting despite symptomatic treatment. On admission he presented body proportions similar to Marfan syndrome. Hypochromic anaemia and positive inflammatory markers were present along with negative results of serologic and microbiological assays. Hormonal parameters, as well as karyotype were normal. Among several imagining procedures, ultrasound and CT of the abdomen revealed areas in the spleen suggestive of proliferative disease or abscesses. Bone marrow examination was normal. Because of high probability of the disease limited to the spleen and deteriorating clinical state of the patient, splenectomy was performed. After the operation significant improvement of the health state of the patient was observed. Histopathological evaluation showed splenic abscesses. However, anamnesis and accessory examinations did not reveal their etiology. This report is an example of possible difficulties in diagnosing splenic abscesses, as well as supports grounds for surgical intervention in chosen cases.
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Tunis Med
January 2025
University of Sfax, Military University Hospital of Sfax, Cardiology Department, Sfax, Tunisia.
Introduction: Nemaline myopathy (NM), also known as Nemalinosis, is a rare congenital muscle disease with an incidence of 1 in 50000. It is characterized by nemaline rods in muscle fibers, leading to muscle weakness. We reported a case of NM revealed by cardiac involvement, and we highlighted the challenges in diagnosing this condition as well as its poor prognosis.
View Article and Find Full Text PDFNutr J
January 2025
Division of Nephrology, State Key Laboratory of Organ Failure Research, Nanfang Hospital, National Clinical Research Center for Kidney Disease, Southern Medical University, 1838 N Guangzhou Ave, Guangzhou, 510515, China.
Background: Iron deficiency is prevalent in patients with chronic kidney disease (CKD), even in those without anemia. However, the effects of iron deficiency on CKD progression and all-cause mortality in non-dialysis-dependent CKD (NDD-CKD) patients without anemia remain incompletely understood.
Methods: This multicenter retrospective nationwide cohort study included adult patients with non-anemia NDD-CKD from 24 hospitals across China.
PLoS One
January 2025
Department of Gastroenterology, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.
Background: It is unclear what impact iron deficiency has on fatigue in people with inflammatory bowel disease (IBD). This systematic review examined the evidence of whether iron deficiency, with or without anaemia, was associated with fatigue in IBD. Fatigue is a common symptom in patients with IBD that can be difficult to manage and treat.
View Article and Find Full Text PDFOrv Hetil
January 2025
1 Semmelweis Egyetem, Általános Orvostudományi Kar, Belgyógyászati és Onkológiai Klinika Budapest, Korányi S. u. 2/a, 1083 Magyarország.
Medicine (Baltimore)
January 2025
School of Medical Laboratory Sciences, Faculty of Health Sciences, Institute of Health, Jimma University, Jimma, Ethiopia.
Anemia is a worldwide public health problem and is associated with platelet disorders. The relationship between anemia and platelets is complex, with the association being either normal platelet count or thrombocytosis. Platelets are significantly decreased in patients with anemia, and thrombocytopenia has been documented in patients with severe anemia.
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