Computerised tomography (CT) is a useful adjunct in the diagnosis of cervical pathology in head and neck carcinoma. However, different criteria used in CT analysis make the comparison of outcome studies difficult. This study compares two different CT criteria (two different lymph node sizes) for detection of cervical lymph node pathology for head and neck tumours in the same patient population. A prospective study was performed on 55 patients, with minimum T2 intraoral squamous cell carcinoma and high risk extraoral malignancies, who underwent 65 neck dissections. Sensitivity, specificity and accuracy of clinical palpation, CT considering lymph nodes larger than 10mm as positive and CT considering lymph nodes larger than 15 mm as positive are compared. The results are as follows: sensitivity, specificity and accuracy of clinical palpation are 86, 84 and 85%, respectively; sensitivity, specificity and accuracy of CT with lymph nodes exceeding 10 mm are 95, 47 and 63%, respectively; sensitivity, specificity and accuracy of CT with lymph nodes exceeding 15 mm are 86, 81 and 83%, respectively. The outcomes of the study reveal that CT evaluation of cervical lymph nodes with a cutoff value of 15 mm should be preferred to a cutoff value of 10mm in order to prevent over-treatment in cervical management of head and neck tumours. When accuracy of the results is considered, CT alone does not have an advantage over clinical palpation in this study.
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http://dx.doi.org/10.1016/j.bjps.2007.05.013 | DOI Listing |
Curr Oncol Rep
January 2025
Radiation Oncology Department, General Regional Hospital "F.Miulli", Acquaviva Delle Fonti, Bari, Italy.
Purpose Of Review: Male breast cancer (MBC) is a rare entity which often arises in elderly people. Aim of this review is to evaluate the principal issues related to MBC in elderly, because the therapeutic management of disease is not only related to the biological behavior of the tumor, but also to the comorbidities and frailty of older population. A scoping literature review was performed on Pubmed and Cochrane Database using the following keywords: therapeutic management/ male/ breast cancer/ elderly patients.
View Article and Find Full Text PDFRev Gastroenterol Peru
January 2025
Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú; Universidad San Ignacio de Loyola, Lima, Perú.
Unlabelled: Endoscopic submucosal dissection (ESD) is the technique of choice in the management of early gastric cancer. Recently, it is also considered as an absolute indication in selected cases of early undifferentiated gastric cancer (U-EGC).
Objectives: In the present study, the first documented cases of ESD in patients with U-EGC are presented and analyzed.
BMC Surg
January 2025
Department of Cardiothoracic Surgery, Fifth Affiliated Hospital of Sun Yat-Sen University, No.52 East Meihua Road, Zhuhai, Guangdong Province, 519000, China.
Background: Laparoscopic-assisted single-port mediastinoscopic esophagectomy is a safe and effective emerging minimally invasive esophagectomy, but little has been reported about the learning curve for this technology. The goal of the study was to determine the number of procedures to achieve different levels of proficiency on the learning curve.
Methods: This study retrospectively analyzed data from consecutive surgeries performed by the same surgeon at the same center from 2016 to 2021.
J Cancer Res Clin Oncol
January 2025
Medical Research Center, Binzhou Medical University Hospital, Binzhou, Shandong, 256600, P.R. China.
Purpose: Immune checkpoint blockades (ICBs) are promising, however they do not fit all types of tumor, such as those lack of tumor antigens. Induction of potent anti-tumor T cell immunity is critical for cancer therapy. In this study, we investigated the efficacy of immunotherapy via the immunogenic cell death (ICD) dying tumor cells in mouse models of lung metastasis and tumorigenesis.
View Article and Find Full Text PDFInt J Surg Case Rep
January 2025
Department of Pathology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province 250025, China. Electronic address:
Introduction And Importance: Retiform hemangioendothelioma(RH) is a rare vascular tumor affecting patients over a wide age range without a gender predilection; only about 50 cases have been described so far.
Case Presentation: We report a case of submandibular retiform hemangioendothelioma in a 58-year-old woman who had been diagnosed with RH 20 years ago and had experienced recurrence four times during the past 20 years. This will increase the limited number of such cases in the hope of gaining a better understanding of this rare type of tumor.
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