A 56-year-old male who was 12 months status post liver transplant presented with a 2-month history of painful, erythematous nodules over the right knee. Several biopsies yielded a mold initially phenotypically identified as a Penicillium species, but molecular sequence analysis ultimately determined the identity as Paecilomyces lilacinus. Several courses of oral voriconazole were required for resolution of the infection. A review of the literature revealed that Paecilomyces species are an infrequent cause of disease in transplant patients, with skin and soft tissue infections being the most common presentation. It is important to accurately identify these infections, and polymerase chain reaction assay using universal fungal primers offers a rapid and precise diagnostic approach. Treatment of Paecilomyces infections may require multiple courses of antifungal therapy, often with surgical debridement. We suggest that voriconazole may be a useful treatment alternative to the more traditional therapy with amphotericin B-based agents.
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http://dx.doi.org/10.1111/j.1399-3062.2007.00248.x | DOI Listing |
Biology (Basel)
January 2025
Plant Protection Department, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.
This study investigates the nematicidal efficacy of strain (AUMC 10620) combined with avermectin (B1a and B1b) against the citrus nematode , both in vitro and in vivo. Laboratory experiments tested four concentrations of (2.5, 5, 10, and 15 × 10 spores/mL) mixed with 250 ppm avermectin, assessing their effects on nematode juveniles (J2) and eggs.
View Article and Find Full Text PDFArch Microbiol
January 2025
Engineering Research Center of Biological Control, Ministry of Education and Guangdong Province, South China Agricultural University, Guangzhou, 510642, China.
Multiple studies have been conducted to investigate the impact of space conditions on human, plant, and microbial life. This research investigated the virulence of spaceflight mutants of the entomopathogenic fungus Purpureocillium lilacinum (HP7, HP36, HP52) and its original strain (SP535) against Tetranychus cinnabarinus as well as examination of the T. cinnabarinus immune response, including alterations in enzyme profiles and microbiome composition post fungal application.
View Article and Find Full Text PDFMicroorganisms
December 2024
Federal Research Center of Biological Plant Protection, p/o 39, 350039 Krasnodar, Russia.
The primary aim of this research was to study the effectiveness of various strains of antagonist microorganisms and biological preparations against , in addition to their impact on the quality of tomato fruits and crop structure. Four microorganism strains and three registered environmentally safe nematicides were used in the experiment presented herein. The results showed that the strains F-22BK/6 and F-22BK/4 had the greatest biological efficacy, reducing the number of galls on tomato plants by 91.
View Article and Find Full Text PDFInt J Phytoremediation
December 2024
Key Laboratory of the Evaluation and Monitoring of Southwest Land Resources (Ministry of Education), Sichuan Normal University, Chengdu, China.
The combined microbial-plant remediation has increasingly been used to remediate heavy metal-contaminated soil. Some microorganisms could enhance phytoremediation efficiency by solubilizing heavy metal and improve plant growth by producing phytohormones in the heavy metal contaminated soils. In the present study, a strong cesium (Cs)-tolerant fungal strain was identified from soil microorganisms contaminated with Cs, and the enrichment conditions for Cs were optimized.
View Article and Find Full Text PDFParasit Vectors
December 2024
Department of Biological Sciences, Florida International University, 11200 SW 8th St, Miami, FL, 33199, USA.
Background: Malaria remains a critical disease. Leucinostatins from the fungus Purpureocillium lilacinum inhibited the transmission of Plasmodium falciparum to mosquitoes via contact.
Methods: Here, we modified the leucinostatin B (LB) C-terminus to make derivatives and examined their inhibition against malaria transmission to mosquitoes.
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