In this paper, a Bayesian wavelet-based denoising procedure for multicomponent images is proposed. A denoising procedure is constructed that (1) fully accounts for the multicomponent image covariances, (2) makes use of Gaussian scale mixtures as prior models that approximate the marginal distributions of the wavelet coefficients well, and (3) makes use of a noise-free image as extra prior information. It is shown that such prior information is available with specific multicomponent image data of, e.g., remote sensing and biomedical imaging. Experiments are conducted in these two domains, in both simulated and real noisy conditions.
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http://dx.doi.org/10.1109/tip.2007.899598 | DOI Listing |
Bioengineering (Basel)
December 2024
Center of Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY 10016, USA.
Non-linear least squares (NLS) methods are commonly used for quantitative magnetic resonance imaging (MRI), especially for multi-exponential T1ρ mapping, which provides precise parameter estimation for different relaxation models in tissues, such as mono-exponential (ME), bi-exponential (BE), and stretched-exponential (SE) models. However, NLS may suffer from problems like sensitivity to initial guesses, slow convergence speed, and high computational cost. While deep learning (DL)-based T1ρ fitting methods offer faster alternatives, they often face challenges such as noise sensitivity and reliance on NLS-generated reference data for training.
View Article and Find Full Text PDFRSC Adv
January 2025
State Key Laboratory of Crystal Materials, Shandong University Jinan Shandong 250100 P.R. China
Individual theranostics with an integrated multifunction holds considerable promise for clinical application compared with multicomponent regimes. MnO nanoparticles with an ultrasmall size (4 nm) and mass production capability were developed with dual function of integrated tumor magnetic resonance imaging (MRI) and therapy. The high valence state of MnO nanocrystals enables a sensitive reaction with the glutathione (GSH) molecule and favorable decomposition ability, which further induces a unique, favorable, variable turn-off and turn-on MRI property.
View Article and Find Full Text PDFBrain Commun
January 2025
Department of Clinical Psychology and Psychobiology, Universidade de Santiago de Compostela (USC), Santiago de Compostela 15782, Spain.
Previous research has revealed patterns of brain atrophy in subjective cognitive decline, a potential preclinical stage of Alzheimer's disease. However, the involvement of myelin content and microstructural alterations in subjective cognitive decline has not previously been investigated. This study included three groups of participants recruited from the Compostela Aging Study project: 53 cognitively unimpaired adults, 16 individuals with subjective cognitive decline and hippocampal atrophy and 70 with subjective cognitive decline and no hippocampal atrophy.
View Article and Find Full Text PDFMagn Reson Med
January 2025
Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Purpose: To develop a deep subspace learning network that can function across different pulse sequences.
Methods: A contrast-invariant component-by-component (CBC) network structure was developed and compared against previously reported spatiotemporal multicomponent (MC) structure for reconstructing MR Multitasking images. A total of 130, 167, and 16 subjects were imaged using T, T-T, and T-T- -fat fraction (FF) mapping sequences, respectively.
Biomolecular condensates formed via phase separation of proteins and nucleic acids are crucial for the spatiotemporal regulation of a diverse array of essential cellular functions and the maintenance of cellular homeostasis. However, aberrant liquid-to-solid phase transitions of such condensates are associated with several fatal human diseases. Such dynamic membraneless compartments can contain a range of molecular chaperones that can regulate the phase behavior of proteins involved in the formation of these biological condensates.
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