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Toward cognitive models of misophonia.
Hear Res
January 2025
Department of Psychology, Concordia University, Montreal, QC, Canada; International Laboratory for Brain, Music and Sound Research (BRAMS), Montreal, QC, Canada; Centre for Research on Brain, Language and Music (CRBLM), Montreal, QC, Canada. Electronic address:
Misophonia is a disorder in which specific common sounds such as another person breathing or chewing, or the ticking of a clock, cause an atypical negative emotional response. Affected individuals may experience anger, irritability, annoyance, disgust, and anxiety, as well as physiological autonomic responses, and may find everyday environments and contexts to be unbearable in which their 'misophonic stimuli' (often called 'trigger sounds') are present. Misophonia is gradually being recognized as a genuine problem that causes significant distress and has negative consequences for individuals and their families.
View Article and Find Full Text PDFA TTPA deletion is associated with Retinopathy with Vitamin E Deficiency (RVED) in the English Cocker Spaniel Dog.
G3 (Bethesda)
January 2025
Canine Genetics Centre, Department of Veterinary Medicine, University of Cambridge, Cambridgeshire, CB3 0ES, UK.
Retinopathy with Vitamin E Deficiency (RVED) is a familial disease in the English Cocker Spaniel (ECS) dog breed. Ophthalmic abnormalities observed in RVED-affected ECS include lipofuscin granule deposition within the tapetal fundus and subsequent retinal degeneration resulting in visual deficits. Affected dogs may also exhibit neurological signs that include ataxia and hindlimb proprioceptive deficit.
View Article and Find Full Text PDFBackground：Neurological deterioration following acute ischemic stroke (AIS) is a common clinical phenomenon associated with poor clinical outcomes. However, neurological deterioration can be attributed to diverse mechanisms in different clinical contexts. Further, there is still a lack of standard and well-recognized definitions of neurological deterioration, which compounds the complexities and challenges of its early identification and management of neurological deterioration.
View Article and Find Full Text PDFApathy in Alzheimer's disease: Eye movements characteristics and neurostructural basis.
J Affect Disord
January 2025
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; Center for Cognitive Neurology, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. Electronic address:
Background: We sought to evaluate the characteristics of eye movements in Alzheimer's disease (AD) patients with apathy (AD-A) and their ability to identify AD-A and explore the shared neurostructure of eye movements and apathy.
Methods: Total 32 normal controls, 36 AD-A and 72 AD with no apathy (AD-NA) patients were recruited. Parameters of smooth pursuit, fixation, prosaccade and antisaccade were compared among the three groups.
Phenolic Compounds and Pharmacological Potential of Extracts for the Treatment of Neurodegenerative Diseases.
Plants (Basel)
January 2025
Department of Pharmaceutical Chemistry, National University of Pharmacy, 61168 Kharkiv, Ukraine.
The search for neuroprotective compounds in lavender is driven by its traditional use for brain health, with antioxidant activity serving as a key mechanism in reducing oxidative stress and supporting cognitive function. Lavender's potential to protect neurons is based on its calming, anti-stress properties, which increase the brain's resistance to neurodegeneration. Although lavender is not a traditional medicinal plant in Ukraine, it is increasingly recognised for its medicinal properties and is widely cultivated in the country.
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