Objective: Two recently described tests of the vestibular system, vestibular evoked myogenic potentials (VEMPs) and ocular vestibular evoked myogenic potentials (OVEMPs), test the descending and ascending vestibular brainstem pathways, respectively. We describe a case of a patient in whom these investigations localised the lesion and suggested its nature.
Methods: VEMPs (to clicks and short duration galvanic stimulation) and OVEMPs (to clicks) were recorded.
Results: Click- and galvanic-evoked VEMPs were delayed on the left side (by approximately 5-6 ms), and click-evoked OVEMPs were similarly delayed (by approximately 4 ms) following left-sided stimulation. Repeat testing 21 months later showed partial resolution.
Conclusions: The observed delays in evoked potentials suggested a demyelinating lesion. Furthermore, the similarity in delayed responses to neck and extraocular muscles was suggestive of a lesion at the root entry zone of the vestibulocochlear nerve.
Significance: VEMPs and OVEMPS may thus provide information about the location and nature of lesions affecting central vestibular pathways.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.clinph.2007.05.068 | DOI Listing |
Int J Mol Sci
January 2025
Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Inha University, Incheon 22332, Republic of Korea.
Gravitational changes have been shown to cause significant abnormalities in various body systems, including the cardiovascular, immune, vestibular, and musculoskeletal systems. While numerous studies have examined the response of the vestibular system to gravitational stimulation, research on functional changes in the peripheral inner ear remains limited. The inner ear comprises two closely related structures: the vestibule and cochlea.
View Article and Find Full Text PDFBrain Sci
December 2024
Neuroscience Center Zurich, University and ETH Zurich, CH-8091 Zurich, Switzerland.
Background/objectives: The auditory middle-latency responses (AMLRs) assess central sensory processing beyond the brainstem and serve as a measure of sensory gating. They have clinical relevance in the diagnosis of neurological conditions. In this study, magnitude and habituation of the AMLRs were tested for sensitivity and specificity in classifying dizzy patients with vestibular migraine (VM) and post-concussive syndrome.
View Article and Find Full Text PDFClin Neurophysiol
January 2025
Ghent University, Department of Rehabilitation Sciences, Corneel Heymanslaan 10 9000 Ghent, Belgium; Ghent University Hospital, Department of Otorhinolaryngology, Corneel Heymanslaan 10 9000 Ghent, Belgium.
Objective: The study aimed to explore the vestibular function in children with neurodevelopmental disorders (NDDs).
Methods: Twenty-eight participants with a NDD (6 girls, 22 boys; 6-13 years; 9;3 ± 2;4 years) were enrolled in this pilot study. Sixteen participants had a single NDD (Autism Spectrum Disorder: n = 7, Developmental Coordination Disorder: n = 3; Attention Deficit/Hyperactivity Disorder: n = 6), the remaining 12 had comorbid NDDs.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
January 2025
Department of Otology Medicine, Shandong Provincial ENT Hospital, Shandong University, Jinan250022, China.
To analyse the 3D-Flair MRI manifestations of the inner ear, vestibular function status, and their correlation with hearing treatment outcomes in patients with severe sudden sensorineural hearing loss (SSNHL), and to explore potential prognostic indicators for sudden deafness. The clinical data of adult patients with unilateral profound sudden sensorineural hearing loss were retrospectively analyzed in Otorhinolaryngology Department of Shandong Provincial ENT Hospital from March 2018 to August 2020. Patients were categorized based on the results of their inner ear 3D-Flair MRI into two groups: the normal MRI group and the abnormal MRI group.
View Article and Find Full Text PDFAm J Audiol
January 2025
School of Audiology & Speech Language Pathology, Bharati Vidyapeeth (Deemed to be University), Pune, India.
Purpose: The present study examined masseteric vestibular evoked myogenic potential (mVEMP) responses in children and compared these results with those of adults, using both air- and bone-conduction modes of stimulation.
Method: Fifteen children and fifteen adults with hearing thresholds below 15 dB HL were considered for the study. Ipsilateral 500-Hz narrow-band chirp (NB CE-chirp) evoked mVEMP responses were elicited via a zygomatic montage through both air- and bone-conduction modes of stimulation.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!