Two recent studies in demonstrate that overexpression of proteins required for centriole duplication can not only induce centriole over-duplication in cells containing centrioles, but can also drive centriole assembly in unfertilized eggs that initially lack centrioles. These studies offer a new perspective on the mechanisms that control centriole duplication.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577213 | PMC |
http://dx.doi.org/10.1038/ncb0707-736 | DOI Listing |
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