Aseptic (avascular) necrosis of the femoral head in adults has been associated with a variety of disease entities. It is also recognized as a potential complication of systemic corticosteroid therapy. Inhaled corticosteroids are the first line anti-inflammatory agents for the long term treatment of asthma. However, long term treatment of asthma with inhaled corticosteroids has been accompanied by concern about both systemic and topical side effects. The most worrying potential systemic effects are adrenal insufficiency, growth suppression, glaucoma and osteoporosis. Fluticasone proprionate may be prescribed at higher doses to relieve respiratory symptoms in the belief that it generates fewer side effects than other inhaled steroids. Studies have shown that fluticasone is safer than beclomethasone or budesonide, with limited oral absorption and extensive hepatic first pass metabolism leading to a lower systemic bioavailability. However growth retardation and asymptomatic adrenal suppression in children receiving high-dose fluticasone have been reported. We report a rare case of avascular osteonecrosis of the femoral head associated with the use of long term inhaled fluticasone propionate along with the intranasal application of triamcinolone acetonide.
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December 2024
Clermont Auvergne University, CNRS, IRD, OPGC, Magmas and Volcanoes Laboratory, 63000, Clermont-Ferrand, France.
The new submarine volcano Fani Maoré offshore Mayotte (Comoros archipelago) discovered in 2019 has raised the awareness of a possible future eruption in Petite-Terre island, located on the same 60 km-long volcanic chain. In this context of a renewal of the volcanic activity, we present here the first volcanic hazard assessment in Mayotte, focusing on the potential reactivation of the Petite-Terre eruptive centers. Using the 2-D tephra dispersal model HAZMAP and the 1979 - 2021 meteorological ERA-5 database, we first identify single eruptive scenarios of various impacts for the population of Mayotte.
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December 2024
Department of Urology, The Jikei University School of Medicine, Kashiwa Hospital, Kashiwashita 163-1, Kashiwa, Chiba, 277-8567, Japan.
To evaluate the safety and efficacy of the Saroa Surgical Robot System in robot-assisted laparoscopic radical prostatectomy (RARP). We enrolled 60 patients who underwent RARP using either the Saroa (n = 9) or da Vinci Xi (n = 51) systems at Jikei University Kashiwa Hospital from January 2022 to March 2024. We compared preoperative characteristics, perioperative outcomes, complications, and postoperative urinary continence at three months between the two groups.
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December 2024
Jihua Laboratory, Foshan, 528000, China.
Surface-enhanced Raman scattering (SERS) technology has attracted more and more attention due to its high sensitivity, low water interference, and quick measurement. Constructing high-performance SERS substrates with high sensitivity, uniformity and reproducibility is of great importance to put the SERS technology into practical application. In this paper, we report a simple fabrication process to construct dense silver-coated PMMA nanoparticles-on-a-mirror SRES substrates.
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December 2024
Department of Environmental Science and Engineering, Faculty of Natural Resources, University of Jiroft, Jiroft, Iran.
This study investigates the potential impacts of climate change on the distribution of Iranian amphibian species and identifies refugia and biodiversity hotspots to inform effective conservation strategies. The study employed ensemble species distribution models to assess the impacts of climate change on 19 Iranian amphibian species. We analyzed future scenarios (2041-2060 & 2081-2100) under a high-emission pathway to identify potential range shifts and refugia (areas with stable or newly suitable climate).
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December 2024
Department of Theoretical Electrical Engineering and Diagnostics of Electrical Equipment, Institute of Electrodynamics, National Academy of Sciences of Ukraine, Beresteyskiy, 56, Kyiv-57, 03680, Kyiv, Ukraine.
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