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| http://dx.doi.org/10.1136/jcp.2007.048702 | DOI Listing |
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Endoscopic annular chondroperichondrial tympanoplasty, technical description.
Eur Arch Otorhinolaryngol
January 2025
Hatay Mustafa Kemal University Otorhinolaryngology Department, Hatay, Turkey.
Purpose: Tympanoplasty is a surgical procedure performed to cure middle ear infections and restore normal middle ear function. It is one of the most common procedures in otological surgery. Since Wullstein described tympanoplasty, the microscope has been a widely used surgical tool in otological surgery.
View Article and Find Full Text PDFSalt-Compact Albumin as a New Pure Protein-based Biomaterials: From Design to In Vivo Studies.
Adv Healthc Mater
January 2025
Inserm UMR_S 1121, CNRS EMR 7003, Université Strasbourg, Biomaterials and Bioengineering, Centre de Recherche en Biomédecine de Strasbourg, Strasbourg, F-67000, France.
Current biodegradable materials are facing many challenges when used for the design of implantable devices because of shortcomings such as toxicity of crosslinking agents and degradation derivatives, limited cell adhesion, and limited immunological compatibility. Here, a class of materials built entirely of stable protein is designed using a simple protocol based on salt-assisted compaction of albumin, breaking with current crosslinking strategies. Salt-assisted compaction is based on the assembly of albumin in the presence of high concentrations of specific salts such as sodium bromide.
View Article and Find Full Text PDFBiomimetic bone cartilage scaffolds based on trilayer methacrylated hydroxyapatite/GelMA composites for full-thickness osteochondral regeneration.
Int J Biol Macromol
January 2025
Department of Pharmaceutical Analysis, Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, The School of Pharmacy, Fujian Medical University, Fuzhou 350122, China. Electronic address:
Since cartilage injury is often accompanied by subchondral bone damage, conventional single-phase materials cannot accurately simulate the osteochondral structure or repair osteochondral injury. In this work, a gradient gelatin-methacryloyl (GelMA) hydrogel scaffold was constructed by a layer-by-layer stacking method to realize full-thickness regeneration of cartilage, calcified cartilage and subchondral bone. Of note, to surmount the inadequate mechanical property of GelMA hydrogel, nanohydroxyapatite (nHA) was incorporated and further functionalized with hydroxyethyl methacrylate (nHA-hydroxyethyl methacrylate, nHAMA) to enhance the interfacial adhesion with the hydrogel, resulting in better mechanical strength akin to human bone.
View Article and Find Full Text PDFEndoscopic butterfly cartilage myringoplasty: our long term results.
Acta Otolaryngol
January 2025
Medical Faculty, Department of Otorhinolaryngology, Recep Tayyip Erdogan University, Rize, Turkey.
Background: Myringoplasty is one of the treatments used for perforated tympanic membrane.
Aim/objective: We aimed to evaluate the long-term anatomical and functional outcomes of patients who underwent endoscopic inlay butterfly cartilage myringoplasty.
Material And Methods: We retrospectively analyzed 74 patients who had undergone endoscopic butterfly cartilage myringoplasty were followed for at least five years.
Spinal instrumentation length affects adjacent segment range of motion and intradiscal pressure.
Sci Rep
December 2024
Institute of Orthopaedic Research and Biomechanics, Trauma Research Centre Ulm, Ulm University Medical Centre, Helmholtzstraße 14, 89081, Ulm, Germany.
Scoliosis instrumentation length depends on the type and degree of deformity and the individual preference of the surgeon. This in vitro study aimed to explore effects of increasing instrumentation length on adjacent segment mobility and intervertebral disc loading. Six fresh frozen human spine specimens (C7-sacrum) with entire rib cage from young adult donors (26-45 years) were loaded with pure moments of 5 Nm.
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