Purpose: Monovision is a method of correction for presbyopia. We have reported the advantage of conventional monovision (the dominant eye is corrected for distance). In this study, we investigated the influence of interocular imbalance of dominancy on the visual function.
Subjects And Methods: Ten healthy subjects without any ophthalmologic disease participated. After cycloplegia, the eyes of the subjects were corrected by soft contact lenses with an artificial pupil (diameter: 3.0mm). The dominant eye was corrected for distance, and the difference in lens power between the lenses was 2.5 D. The subjects were classified into two groups by strength of the imbalance of sensory dominance, which was determined by using binocular rivalry. Binocular visual functions (visual acuity at various distances, contrast sensitivity, near stereoacuity) were compared between the two groups.
Results: Subjects with strong imbalance of sensory dominance showed decreased near visual acuity as well as decreased binocular summation of contrast sensitivity at low spatial frequencies. On the other hand, near stereoacuity was not affected by the imbalance of sensory dominance.
Conclusion: These results suggest that strong imbalance of sensory dominance interferes with binocular visual functions in monovision. Thus, the evaluation of ocular dominance is crucial for clinical applications of monovision.
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Zhongguo Zhen Jiu
January 2025
Department of Acupuncture-Moxibustion and Rehabilitation, Jiangsu Provincial Hospital of TCM, Nanjing 210029, China.
Objective: To explore the efficacy of acupuncture based on "gut-brain axis" combined with sensory integration training in children with autism spectrum disorder (autism) and its effect on gastrointestinal symptoms.
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Toxics
December 2024
Shanxi Key Laboratory of Coal-Based Emerging Pollutant Identification and Risk Control, Research Center of Environment and Health, College of Environment and Resource, Shanxi University, Taiyuan 030006, China.
As one of the most common air pollutants, fine particulate matter (PM) increases the risk of diseases in various systems, including the urinary system. In the present study, we exposed male and female C57BL/6J mice to PM for 8 weeks. Examination of renal function indices, including creatinine (CRE), blood urea nitrogen (BUN), uric acid (UA), and urinary microalbumin, indicated that the kidneys of female mice, not male mice, underwent early renal injury, exhibiting glomerular hyperfiltration.
View Article and Find Full Text PDFPharmaceuticals (Basel)
November 2024
Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, Coyoacán, Ciudad de Mexico 04510, Mexico.
Trigeminal neuralgia (TN) is chronic pain caused by damage to the somatosensorial system on the trigeminal nerve or its branches, which involves peripheral and central dysfunction pain pathways. Trigeminal pain triggers disruptive pain in regions of the face, including within and around the mouth. Besides clinical experiences, translating the language of suffering into scientific terminology presents substantial challenges.
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December 2024
Department of Diabetes, Nutrition and Metabolic Diseases, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Background: Diabetes mellitus is closely related to periodontal disease and dental lesions, disorders which through dental infection and metabolic imbalance become negatively potentiated and cause a vicious circle that is almost impossible to break. The aim of this research was to study if the severity of dental and periodontal lesions is related to the presence of microvascular complications and glycemic control in patients with type 2 diabetes mellitus (T2DM).
Methods: In total, 112 subjects with T2DM that underwent a dental evaluation were enrolled in this case-control study.
Biomedicines
December 2024
Department of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy.
Background: Pimozide is a conventional antipsychotic drug of the diphenylbutylpiperidine class, widely used for treating schizophrenia and delusional disorders and for managing motor and phonic tics in Tourette's syndrome. Pimozide is known to block dopaminergic D2 receptors and various types of voltage-gated ion channels. Among its side effects, dizziness and imbalance are the most frequently observed, which may imply an effect of the drug on the vestibular sensory receptors, the hair cells.
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