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Single- vs. dual-head SPECT for detection of myocardial ischemia and viability in a large study population. | LitMetric

AI Article Synopsis

  • The study analyzed the effectiveness of single-head versus dual-head gamma cameras in thallium-201 myocardial SPECT for diagnosing heart conditions in 1334 patients.* -
  • Results showed that dual-head cameras had a higher positive predictive value for detecting myocardial scar tissue and greater sensitivity for diagnosing ischemia in certain heart regions, while single-head cameras had better specificity.* -
  • Despite single-head cameras being more specific, the dual-head technique is recommended for routine clinical use because it reduces the acquisition time, leading to increased efficiency in patient care.*

Article Abstract

Background: As single-head data acquisition for thallium-201 myocardial SPECT is a frequently used method mainly in the outpatient medical care as well as in smaller hospitals, comparison to dual-head data collection is a still discussed issue mainly with regard to quality control and -assurance.

Methods: A total of 1334 patients undergoing thallium-201 myocardial SPECT for diagnosis of myocardial ischemia and/or viability have been retrospectively analyzed. In 554 patients, a single-head gamma camera (360 degrees rotation) has been applied, whereas a dual-head gamma camera (180 degrees rotation) has been used in 780 patients. Four hundred twenty-six patients received both myocardial SPECT as well as coronary angiography. The diagnostic value of both applied acquisition techniques has been analyzed.

Results: Regarding myocardial viability, positive predictive value for the diagnosis of myocardial scar tissue was significantly higher for dual-head- as compared to single-head acquisition. Among the 426 patients undergoing diagnosis of myocardial ischemia, significant differences have only been found with regard to specificity being higher in the single-head acquisition. Diagnosis of myocardial ischemia related to a distinct myocardial perfusion region showed a significantly higher sensitivity of dual-head acquisition for the left anterior descending perfusion area, whereas specificity was significantly higher for single-head acquisition.

Conclusions: Our results indicate a beneficial effect of dual-head data collection with regard to sensitivity of the diagnosis of myocardial ischemia. In contrast, single-head data acquisition was superior with regard to specificity. However, it is justified to preferably apply dual-head data collection in clinical routine due to the shorter acquisition time leading to an evident time benefit of this acquisition technique.

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Source
http://dx.doi.org/10.1016/j.clinimag.2007.02.025DOI Listing

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