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Comparison of neutral and sniffing position for ease of endotracheal intubation using Airtraq optical laryngoscope-A randomized trial.
J Anaesthesiol Clin Pharmacol
August 2024
Department of Anesthesia and Critical Care, Pt. B. D. Sharma PGIMS, Rohtak, Haryana, India.
Background: Traditionally, the sniffing position has been considered a standard head and neck position during direct laryngoscopy. The perfect head and neck position for video laryngoscopy has yet not been described. Hence, we planned the present study to compare the neutral and sniffing position for ease of intubation using Airtraq.
View Article and Find Full Text PDFCrouching bacteria, hidden tetA genes in natural waters: Intracellular damage via double persulfate activation (UVA/Fe/PDS) effectively alleviates the spread of antibiotic resistance.
J Hazard Mater
December 2024
Universidad Politécnica de Madrid (UPM), E.T.S. de Ingenieros de Caminos, Canales y Puertos, Departamento de Ingeniería Civil: Hidráulica, Energía y Medio Ambiente, Unidad docente Ingeniería Sanitaria, c/ Profesor Aranguren, s/n, ES-28040 Madrid, Spain.
In this study, we elucidated the chemical and biological inactivation mechanisms of peroxydisulfate (PDS) activated by UVA and Fe (UVA/Fe/PDS) in wild-type antibiotic-resistant bacteria (ARB) isolated from a river in Inner Mongolia. Among the screened wild-type ARB, the relative abundance of unidentified Enterobacteriaceae, Stenotrophomonas, and Ralstonia was high. A ratio of 1:1 for Fe and PDS under 18 W·m UVA radiation (sunny days) completely inactivated the environmental ARB isolates.
View Article and Find Full Text PDFTherapeutic Response to PRRNT in a Rare Case of Metastatic Renal Neuroendocrine Carcinoma.
World J Nucl Med
June 2024
Department of Pathology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
Article Synopsis
- Neuroendocrine tumors (NETs) are rare cancers that can be tricky to treat because they behave differently and are not well understood.
- A specific case involved a patient with a rare and aggressive type of kidney NET that continued to worsen despite surgery and chemotherapy.
- The patient improved significantly after receiving a new type of treatment called PRRNT, which used a special medicine to target the tumor, and they are stable now.
Two by Two Factorial Design using Metformin and Curcumin for Second Primary Head and Neck Cancer Prevention Trial.
Asian Pac J Cancer Prev
June 2024
Department of Head and Neck Oncology, Mazumdar Medical Center, Narayana Health City, Bangalore, India.
Objective: The 2x2 factorial design is an effective method that allows for multiple comparisons, especially in the context of interactions between different interventions, without substantially increasing the required sample size. In view of the considerable preclinical evidence for Curcumin and Metformin in preventing the development and progression of head and neck squamous cell carcinoma (HNSCC), this study describes the protocol of the clinical trial towards applying the drug combination in prevention of second primary tumors.
Methods: We have applied the trial design to a large phase IIB/III double-blind, multi-centric, placebo-controlled, randomized clinical trial to determine the safety and efficacy of Metformin and Curcumin in the prevention of second primary tumours (SPT) of the aerodigestive tract following treatment of HNSCC (n=1,500) [Clinical Registry of India, CTRI/2018/03/012274].
A photoaging smartphone application to promote sun safety behaviors among youth in late childhood and adolescence.
Pediatr Dermatol
July 2024
Department of Dermatology and Cutaneous Surgery, USF Health Morsani College of Medicine, Tampa, Florida, USA.
Article Synopsis
- - The study investigated how a smartphone app designed to show the effects of UV exposure on skin can encourage young people to adopt better sun safety habits.
- - Participants, mostly around 14 years old, reported their sun exposure behaviors before and after using the app, with the majority acknowledging that the app increased their motivation to practice sun safety.
- - Overall, the results indicate that using a photoaging application could be an effective way to promote sun protection among youth, potentially reducing their risk of skin cancer later in life.
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