Background. Idiopathic scoliosis is one of the most often diagnosed by orthopaedists forms of spine cord deformations. Our knowledge about epidemiology and aetiology of this disease is still not broad enough. Authors have focused on the analysis of a factor that may influence initiation and progress of scoliosis. Material and methods. Levels of estradiol in healthy and scoliotic girls aged 11-14 have been compared. Medium angle of the curve measured in Cobb's classification was 33 degrees 11 degrees (10 degrees -60 degrees ). Results. Comparison of analysed parameters between both groups has shown significant differences in estradiol levels. Medium level of the hormone in the control group was 50,030 pg/ml (sx=18,586) and was significantly higher than the level of hormone in the group of children with scoliosis where it equalled 28,201 pg/ml (sx=15,628). Conclusion. These results indicate a possible influence of estradiol secretion disorders during gender development on initiation and progression of the lateral curvature of the spine.
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