Indium(III) trifluoromethanesulfonate as an efficient catalyst for the deprotection of acetals and ketals.

J Org Chem

Department of Medicinal Chemistry, AMRI, Albany, NY 12203, USA.

Published: July 2007

Acetals and ketals are readily deprotected under neutral conditions in the presence of acetone and catalytic amounts of indium(III) trifluoromethanesulfonate (<0.8 mol %) at room temperature or mild microwave heating conditions to give the corresponding aldehydes and ketones in good to excellent yields.

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http://dx.doi.org/10.1021/jo0707075DOI Listing

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