The goal of the present study was to develop a new dose-volume histogram (DVH)- based homogeneity index for effectively evaluating the dose homogeneity of intensity-modulated radiotherapy plans. The new index, called the sigma-index ("S-index") is defined as the standard deviation of the normalized differential DVH curve. In a study of 16 patients with brain tumors at our institution, the S-index was found to vary from 0.80 to 3.15. Our results showed that the S-index provides a more reliable and accurate measure of dose homogeneity than that given by conventional methods. A guideline for evaluating the dose homogeneity of treatment plans based on the S-index and its relation to equivalent uniform dose is discussed.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722417 | PMC |
| http://dx.doi.org/10.1120/jacmp.v8i2.2390 | DOI Listing |
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