Unlabelled: Otogenous lateral sinus thrombosis (OLST) is a rare disease and presents a controversial treatment.
Aim: Clinical aspects and treatment were reported based on our experience.
Methods: Retrospective study. Six cases of OLST were treated in our institution in the last ten years. Clinical and imaging data were analyzed.
Results: All six patients had the lateral sinus thrombosis detected during image evaluation for other symptoms related to chronic otitis media (COM) complications. Fever, headache and facial paralysis were the main clinical manifestation related to mastoiditis, meningitis and cerebellar abscess. We could not identify, in any case, specific features of lateral sinus thrombosis. In all cases a mastoidectomy was associated with large spectrum antibiotics maintained for 3 months. In three cases anticoagulation therapy was introduced and in three cases anticoagulation was not indicated. All cases presented a good clinical evolution, without sequelae.
Conclusions: OLST is almost always associated with other complications of COM. It is diagnosed almost by accident during the investigative image study. We believe such disease is underestimated. In our experience, OLST presents a benign course, and mastoidectomy with antibiotics is the treatment of choice.
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http://dx.doi.org/10.1016/s1808-8694(15)31062-4 | DOI Listing |
JACC Case Rep
December 2024
Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, Hong Kong.
A 62-year-old man with acute coronary syndrome underwent an echocardiogram for evaluation. A transthoracic echocardiogram revealed masses within a giant coronary sinus. This case highlights the role of multimodality imaging in investigating coronary sinus enlargement, coronary sinus thrombosis, and the approach to management.
View Article and Find Full Text PDFEur J Pediatr
January 2025
Pediatric Unit, Meyer Children's Hospital IRCCS, Via Gaetano Pieraccini 24, 50139, Florence, Italy.
Among acute mastoiditis (AM) complications, cerebral venous sinus thrombosis (CVST) is particularly severe, leading to increased intracranial pressure and potential neurological sequelae. Predicting the development of such complications is challenging. The aims of the present study were to evaluate the incidence, clinical characteristics, and risk factors for the development of CVST in AM.
View Article and Find Full Text PDFNeurosurg Rev
January 2025
Department of Neurosurgery, Beijing Friendship hospital, Capital Medical University, No. 95 Yong 'an Road, Xicheng District, Beijing, China.
Patients with cerebral venous thrombosis (CVT) may experience poor response to anticoagulant therapy and delayed surgical treatment may lead to clinical deterioration. However, the factors contributing to clinical deterioration remain poorly understood. Patients with CVT from three centers between January 2017 and October 2023 were included and grouped as the development cohort and validation cohort.
View Article and Find Full Text PDFJ Matern Fetal Neonatal Med
December 2025
Department of Vascular Surgery & Interventional Therapy, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Background: Pregnancy-associated venous thromboembolism (PA-VTE) seriously threatens maternal health. We aimed to investigate the clinical characteristics, risk factors, treatments, and pregnancy outcomes to better prevent and treat PA-VTE.
Methods: PA-VTE patients were selected from 171,898 women who were registered in the Department of Obstetrics of Fujian Maternity and Child Health Hospital from January 2014 to August 2023 and delivered to calculate the incidence.
PLoS One
January 2025
Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Background: Cerebral venous sinus thrombosis (CVST) is a rare type of thrombosis that affects the cerebral venous system. The data on neurological outcomes are limited.
Objectives: This study aimed to investigate the neurological outcomes of CVST, contributing factors, clinical presentation, treatment and mortality.
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