AI Article Synopsis
- The study examined the effectiveness of oral polio vaccines in Saudi Arabia by testing children’s antibodies post-vaccination.
- Approximately 209 vaccinated children were analyzed, with blood samples collected at nine months to measure their immune response.
- The results showed varying success rates: 79% for Type 1, 88% for Type 2, and 65% for Type 3, indicating a need for a new vaccination strategy.
Article Abstract
This is a national seroprevalence study conducted in Saudi Arabai in 1991G to determine postvaccination poliovirus antibody. Two hundred and nine children vaccinated with three oral polio vaccines at three, four, and five months of age were included in the study representing the five main regions in Saudi Arabia. Blood samples were collected at the age of nine months. Cytopathic effect (CPE) neutralization was used to determine the level of polio antibody. A dilution of 1/8th or more was defined as positive. Seventy-nine percent, 88% and 65% of the children were positive for Type 1, Type 2, and Type 3, respetively. Development of a new strategy of polio vaccination is needed.
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| http://dx.doi.org/10.5144/0256-4947.1994.111 | DOI Listing |
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