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New triterpene glucosides, oligoporins A-C, from Oligoporus tephroleucus protect DNA from Fenton reaction. | LitMetric

AI Article Synopsis

  • New triterpene glucosides named oligoporins A, B, and C were found in the methanolic extract of the fungus Oligoporus tephroleucus.
  • The structures of these compounds were determined using spectroscopic techniques.
  • These compounds showed a strong protective effect against DNA damage caused by hydroxyl radicals generated in a chemical reaction involving hydrogen peroxide and ferrous ions.

Article Abstract

New triterpene glucosides, oligoporins A (1), B (2), and C (3), were isolated from the methanolic extract of the fruiting bodies of Oligoporus tephroleucus (Polyporaceae). Their structures were established by spectroscopic methods. These compounds significantly exhibited protective effect to plasmid DNA damage by hydroxyl radical (*OH) generated from the Fenton reaction with hydrogen peroxide and ferrous.

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Source
http://dx.doi.org/10.1016/j.bmcl.2007.06.034DOI Listing

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