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The Influence of Aging on Hip Abductor Muscle Torque, Power, Velocity and the Association With Lower Limb Physical Function.
J Geriatr Phys Ther
November 2024
Department of Physical Therapy and Rehabilitation Science, University of Maryland School of Medicine, Baltimore, Maryland.
Background And Purpose: Muscle strength, power, and mass decline with aging, leading to functional loss highly correlated with balance and falls in older adults. Lower limb muscle function is critical for fall prevention in older adults, and hip abductor force and rapid force development have been shown to be important during stepping tasks. However, it remains unclear whether hip abductor muscle function changes with aging.
View Article and Find Full Text PDFProteomic analysis of egg production peak and senescence in the ovaries of Taihe black-boned silky fowl (Gallus gallus domesticus Brisson).
BMC Genomics
January 2025
Animal Science College, Zhejiang University, Zijingang Campus, Hangzhou, Zhejiang, 310058, China.
Background: The Taihe black-boned silky fowl, a distinguished indigenous breed of chicken, is renowned for its dual utility in both traditional medicinal and culinary applications. However, the breed faces significant challenges due to its suboptimal reproductive capabilities and a notably brief egg-laying period, which have impeded its broader development and cultivation. In this research endeavor, we employed an advanced, rapid DIA (Data independent acquisition) quantitative proteomics method on the Astral platform to meticulously analyze the ovarian proteome of these chickens.
View Article and Find Full Text PDFDurability of Adaptive Immunity in Immunocompetent and Immunocompromised Patients Across Different Respiratory Viruses: RSV, Influenza, and SARS-CoV-2.
Vaccines (Basel)
December 2024
Department of Medicine, University of Patras, 26504 Rio, Greece.
Background/objectives: Research on respiratory virus immunity duration post-vaccination reveals variable outcomes. This study performed a literature review to assess the efficacy and longevity of immune protection post-vaccination against SARS-CoV-2, influenza, and respiratory syncytial virus (RSV), with a focus on immunocompromised populations. Specific objectives included examining humoral and cellular immune responses and exploring the impact of booster doses and hybrid immunity on extending protection.
View Article and Find Full Text PDFAntigenic Imprinting Dominates Humoral Responses to New Variants of SARS-CoV-2 in a Hamster Model of COVID-19.
Microorganisms
December 2024
KU Leuven, Department of Microbiology, Immunology & Transplantation, Rega Institute, Virology, Antiviral Drug and Vaccine Research Group, Laboratory of Molecular Vaccinology & Vaccine Discovery (MVVD), 3000 Leuven, Belgium.
The emergence of SARS-CoV-2 variants escaping immunity challenges the efficacy of current vaccines. Here, we investigated humoral recall responses and vaccine-mediated protection in Syrian hamsters immunized with the third-generation Comirnaty Omicron XBB.1.
View Article and Find Full Text PDFEffect of Homologous and Heterologous Booster in COVID-19 Vaccination.
Pharmaceuticals (Basel)
December 2024
Institute for Biocides and Medical Ecology, Trebevićka 16, 11030 Belgrade, Serbia.
COVID-19 became a global health crisis in early 2020, and the way out of the crisis was the rapid development of vaccines by Sinopharm, Pfizer, and Sputnik, among others, which played a crucial role in controlling the pandemic. Therefore, this study aims to investigate the long-term immune response by measuring the levels of anti-S1 IgG antibodies induced by homologous and heterologous vaccination regimens. We investigated the titer of the anti-S1 IgG antibody produced for the viral surface antigen 3, 6 months after the second dose, before the third dose, and 1, 3, and 6 months after the third dose.
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