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Current status of drug therapy for chronic hepatitis B.
World J Gastroenterol
January 2025
Division of Liver Surgery, Department of General Surgery and Laboratory of Liver Surgery, and State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
In this editorial, we comment on the article by Meng . Chronic hepatitis B (CHB) is a significant global health problem, particularly in developing countries. Hepatitis B virus (HBV) infection is one of the most important risk factors for cirrhosis and hepatocellular carcinoma.
View Article and Find Full Text PDFOn the Analysis of Protein Genetic Architecture: Response to "Protein sequence landscapes are not so simple".
bioRxiv
December 2024
Department of Ecology and Evolution, University of Chicago, Chicago, IL, USA.
We recently reanalyzed 20 combinatorial mutagenesis datasets using a novel reference-free analysis (RFA) method and showed that high-order epistasis contributes negligibly to protein sequence-function relationships in every case. Dupic, Phillips, and Desai (DPD) commented on a preprint of our work. In our published paper, we addressed all the major issues they raised, but we respond directly to them here.
View Article and Find Full Text PDFConstructing agentive inference as a universal property: Strange functorial things and categorical red queen dynamics: Comment on "Path integrals, particular kinds, and strange things" by K. Friston, L. Da Costa, D. Sakthivadivel, C. Heins, G. Pavliotis, M. Ramstead, and T. Parr.
Phys Life Rev
October 2023
Department of Mathematics, University of California, Riverside, Riverside, CA 92521, USA. Electronic address:
An exciting path ahead: Comment on "Path integrals, particular kinds, and strange things" by Friston K., Da Costa L., Sakthivadivel D.A.R., Heins C., Pavliotis G.A., Ramstead M., and Parr T.
Phys Life Rev
October 2023
Department of Biomedical, Metabolic and Neural Sciences, Neuromorphic Intelligence LABoratory, University of Modena & Reggio Emilia, Modena, Italy. Electronic address:
Understanding the factors that impact federal rulemaking: a survey of former EPA regulators.
Health Aff Sch
October 2024
Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States.
While federal rulemaking is an essential part of American governance, it is not well understood by researchers and advocates. We surveyed 115 former regulators at the Environmental Protection Agency to understand their views on the kinds of information they valued most and their communication preferences (June-August 2023). Respondents highly valued information about the scope of a problem (96%), legal analysis (97%), technology assessments (96%), and impacts of a proposed rule (99%).
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