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Neurotrophins and their receptors in the peripheral nervous system and non-nervous tissue of fish.
Fish Physiol Biochem
January 2025
Centro Tlaxcala de Biología de La Conducta, Universidad Autónoma de Tlaxcala, 90070, Tlaxcala, Mexico.
Trophic factors, such as neurotrophins, are fundamental for cellular processes including differentiation, growth, survival, and regeneration. These molecules exhibit significant morphological and phylogenetic conservation throughout the animal kingdom, indicating conserved functions. In fish, the oldest and most diverse group of vertebrates, neurotrophins, and their receptors play pivotal roles not only within the central nervous system but also in various peripheral tissues.
View Article and Find Full Text PDFThe levels of adropin and its therapeutic potential in diabetes.
J Endocrinol
January 2025
K Nowak, Animal Physiology, Biochemistry and Biostructure, Poznan University of Life Sciences, Poznan, Poland.
Adropin, a peptide hormone encoded by the ENHO gene is expressed in various tissues including the brain. Accumulating evidence from in vivo and in vitro studies highlights adropin's pivotal role in modulating carbohydrate and lipid metabolism. Notably, circulating adropin levels are lower in overweight and obese humans and experimental interventions involving adropin overexpression or synthetic administration demonstrate promising outcomes in mitigating obesity-related metabolic abnormalities and preventing weight gain.
View Article and Find Full Text PDFSubstitution and Electron Transfer in Diborane-Quinone Systems.
Chemistry
January 2025
Ruprecht-Karls-Universität Heidelberg, Institut für Anorganische Chemie, Im Neuenheimer Feld 270, 69120, Heidelberg, GERMANY.
The dual reactivity of boron compounds as Lewis acids and electron donors has spurred the development of a metallomimetic chemistry of boron compounds as a topical research theme. In this work we elaborate on the reaction of specially-designed diborane(4) compounds with quinones, as a prime example showing their dual (metallomimetic) chemistry as a Lewis acid and electron donor. The quinone is first coordinated to the diborane and then reduced by intramolecular electron transfer from the B-B bond to a quinone π* orbital.
View Article and Find Full Text PDFPredictive processing: Shedding light on the computational processes underlying motivated behavior.
Behav Brain Sci
January 2025
Donders institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The
Integrating the predictive processing framework into our understanding of motivation offers promising avenues for theoretical development, while shedding light on the computational processes underlying motivated behavior. Here we decompose expected free energy into intrinsic value (i.e.
View Article and Find Full Text PDFAnalysis of hollow visceral injuries admitted to a level one intensive care unit in South Africa.
S Afr J Surg
December 2024
Division of Surgery, Tygerberg Hospital, Stellenbosch University, South Africa.
Background: Bowel trauma, encompassing injuries to the small and large intestine, represents a significant medical challenge due to its potential for morbidity and mortality. Management of bowel injuries remains surgical, but multiple factors influence the outcome in these patients. This study provides an in-depth analysis of the high-risk features of hollow visceral trauma in the ICU setting and the corresponding mortality rates, shedding light on the critical factors that influence outcomes in these cases.
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