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Bacteraemia after transcatheter aortic valve implantation: a nationwide cohort study.
Heart
December 2024
Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Background: Bacteraemia and infective endocarditis (IE) are rare but severe complications of transcatheter aortic valve implantation (TAVI). Limited data exist on the incidence and microbiological profile of early bacteraemia in this population. This study aimed to evaluate the 6-month incidence of bacteraemia, IE and associated mortality following TAVI.
View Article and Find Full Text PDFMortality predictors and definition proposal for complicated coagulase-negative Staphylococcus bacteraemia: a multicentre prospective cohort study.
Clin Microbiol Infect
December 2024
Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario Virgen Macarena, Seville, Spain; Departamentos de Medicina y Microbiología, Facultad de Medicina, Universidad de Sevilla, Seville, Spain; Instituto de Biomedicina de Sevilla/CSIC, Seville, Spain; CIBERINFEC, Instituto de Salud Carlos III, Madrid, Spain. Electronic address:
Objectives: The study aimed to explore a definition for complicated coagulase-negative staphylococci bloodstream infections (CoNS BSIs) and to identify predictors for mortality.
Methods: A prospective cohort study was conducted from October 2016 to March 2017 in 26 Spanish hospitals. Complicated CoNS BSI criteria included lack of early catheter removal in catheter-related cases, foreign indwelling implant, persistent bacteraemia, fever ≥72 hours on active therapy, metastatic infection or deep-seated focus, and infective endocarditis.
Pathogenic spectrum of infective endocarditis and analysis of prognostic risk factors following surgical treatment in a tertiary hospital in China.
BMC Infect Dis
December 2024
Department of Cardiac Surgery, First Affiliated Hospital of Sun Yat-sen University, 58 Zhongshan II Rd, Guangzhou, 510080, China.
Background: This study aimed to summarize the pathogenic spectrum of infective endocarditis (IE) and analyze the risk factors for poor prognosis in surgical patients in a tertiary hospital in China.
Methods: We retrospectively included patients diagnosed with IE between January 2013 and January 2022. The pathogenic spectrum was summarized; the risk factors for early postoperative mortality and embolic events were analyzed using multivariate logistic regression.
Characterization of biofilms through ethyl methanesulfonate mutagenesis.
AIMS Microbiol
October 2024
Department of Biology, University of Nebraska at Kearney, Kearney, NE, United States.
is a coagulase-negative species responsible for a multitude of infections. These infections often resemble those caused by the more pathogenic staphylococcal species, , such as skin and soft tissue infections, prosthetic joint infections, and infective endocarditis. Despite a high mortality rate and infections that differ from other coagulase-negative species, little is known regarding pathogenesis.
View Article and Find Full Text PDFLength of Hospital Stay for Endocarditis Before and After the Partial Oral Treatment of Endocarditis Trial.
J Am Coll Cardiol
December 2024
The Heart Center, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Article Synopsis
- * A study utilizing Danish registries analyzed 4,748 patients with infective endocarditis before and after the POET trial publication, examining changes in hospital length of stay (LOS) and outcomes like mortality and relapse of bacteremia.
- * Results showed a significant decrease in median LOS by 8 days post-POET publication, with no significant change in mortality rates but a notable reduction in relapse of bacteremia from 3.5% to 1.6%.
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