We performed an exploratory study to evaluate 2 self-administered questionnaires assessing hand dermatitis and to investigate a possible exposure-response relation between dermal exposure to semi-synthetic metal working fluids (SMWF) and dermatitis. In a cross-sectional survey on dermatitis, a symptom-based questionnaire and a picture-based skin-screening list were applied in 80 SMWF-exposed workers and 67 referents. To evaluate accuracy of the questionnaires, 47 subjects were examined by a dermatologist. Dermal exposure levels to SMWF were assessed on the hands, forearms, and face with an observational method that was validated with a fluorescent-tracer method. The symptom-based questionnaire had a relatively high sensitivity (0.86) but moderate specificity (0.64), the skin-screening list had a low sensitivity (0.36) and a relatively high specificity (0.84). The skin-screening list seemed to represent the more severe cases of dermatitis and showed a significant relation to exposure, for dermatitis on hands, forearms, or face. In epidemiological surveys where workers are not seen by a dermatologist, the skin-screening list seems to be more appropriate to detect cases of dermatitis, as its higher specificity results in less false positives. Alternatively, it would be preferable to apply the symptom-based questionnaire; workers with symptoms should be seen by a dermatologist to identify false positives.

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http://dx.doi.org/10.1111/j.1600-0536.2007.01127.xDOI Listing

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