Severe granulocytopenia predispose patients with Felty's syndrome to severe infectious diseases. The following report deals with an occurrence of chronic disseminated candidiasis in a patient with Felty's syndrome who presented with prolonged and severe granulocytopenia. To the best of our knowledge this coexistence has never been described before.
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http://dx.doi.org/10.1007/s00296-007-0366-x | DOI Listing |
J Clin Med
December 2024
Rheumatology Department, Virgen Macarena University Hospital, Health Service of Andalucian, 41009 Seville, Spain.
To describe the frequency of neutropenia and Felty syndrome in patients with rheumatoid arthritis (RA) attended in routine clinical practice. We selected by randomization a sample of 270 RA patients attended from January 2014 to November 2022. Demographic, clinical, and neutropenia-related variables were collected from the electronic medical records.
View Article and Find Full Text PDFArch Dermatol Res
December 2024
Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277, Jiefang Avenue, Wuhan, 430022, China.
Objective: We analyzed adverse events (AEs) related to adalimumab and etanercept using the Food and Drug Administration Adverse Event Reporting System (FAERS) to detect unexpected AEs. Subsequently, we compared the discrepancy in serious outcomes involving the same injection site reactions (ISRs) between two different medications.
Methods: Four algorithms, including reporting odds ratio (ROR), proportional reporting ratio (PRR), Bayesian confidence propagation neural network (BCPNN), and the multi-item gamma Poisson shrinker (MGPS) were used to identify AE signals.
J Inflamm Res
November 2024
Department of Rheumatology and Immunology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, People's Republic of China.
Felty's syndrome (FS) is an uncommon disorder with a poor prognosis, and most patients die from infections caused by neutropenia. Currently, there is no standardized treatment strategy, and treatment options are based on case reports and clinical experience. To date, no cases of FS complicated by coronavirus disease-2019 (COVID-19) have been reported.
View Article and Find Full Text PDFCureus
October 2024
Rheumatology, Hospital Universitario Dr. José Eleuterio González, Monterrey, MEX.
Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis characterized by painful skin ulcers. Treatment typically involves systemic corticosteroids, calcineurin inhibitors, or tumor necrosis factor-alpha inhibitors. Currently, treatment guidelines are not well established, making it important to consider alternative options in complicated cases.
View Article and Find Full Text PDFCureus
September 2024
Endocrinology and Metabolism, Institute of Post Graduate Medical Education & Research, Kolkata, IND.
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