Thirteen patients treated with gut decontamination were screened over a period of three years for digestive colonization and acquisition of resistant strains, in fact 297 strains had been isolated from 226 stool cultures within 120 enterobacteria and other species. Our study pointed out a betaLSE digestive colonization rate of 30.8% of the total enterobacteria isolated, these strains exhibit resistance of most beta-lactams especially against third generation cephalosporins. This analysis showed that these strains are endogen and specific for each patient, the common multiresistance resulted from the selective pressure of gut decontamination.

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http://dx.doi.org/10.1016/j.patbio.2006.01.008DOI Listing

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